ArticleTherapeutics and clinical risk management2021
Growth Promoting Effect of Vacuum Sealing Drainage in the Healing Processes of Diabetic Foot Ulcers.
Article in Therapeutics and clinical risk management, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 16 citations in OpenAlex.
- Efficacy and safety of ultrasound-assisted wound debridement in the treatment of diabetic foot ulcers: a systematic review and meta-analysis of 11 randomized controlled trials.Frontiers in endocrinology · 2024Pooled it
- Efficacy of prophylactic negative pressure wound therapy after open ventral hernia repair: a systematic review meta-analysis.BMC surgery · 2023Pooled it
- A meta-analysis on the efficacy of vacuum sealing drainage combined with autologous platelet-rich plasma in the treatment of Grade 2 and Grade 3 diabetic foot ulcers.International wound journal · 2023Pooled it
- [Clinical effects of antibiotic bone cement and VSD combined with free chimeric anterolateral thigh perforator myocutaneous flaps for sequential treatment of diabetic calcaneal osteomyelitis wounds].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2026Article
- Investigation of the effect of debridement combined with antibiotic-loaded bone cement on pain and psychological status in diabetic foot ulcer patients.Frontiers in medicine · 2025Article
- Comparison of customized vacuum sealing drainage and vacuum sealing drainage in the treatment of diabetic foot ulcers: a retrospective analysis.Journal of orthopaedic surgery and research · 2023Article
- Negative pressure wound therapy for flap closed-incisions after 3D-printed prosthesis implantation in patients with chronic osteomyelitis with soft tissue defects.BMC musculoskeletal disorders · 2023Article
- Application of VSD technique in adults with chronic osteomyelitis of the extremities combined with soft tissue defects.International wound journal · 2023Article
- Roles of negative pressure wound therapy for scar revision.Frontiers in physiology · 2023Review
- Effect of vacuum sealing drainage plus skin grafting on deep burns and analysis of risk factors for postoperative infection.American journal of translational research · 2022Article
Corrections and comments
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo explore the growth-promoting effect of vacuum sealing drainage (VSD) during the healing processes of diabetic foot ulcers (DFUs).
methodsFrom November 2018 to December 2019, 38 patients with unilateral DFUs were enrolled in this retrospective study. All patients were divided into two groups according to the use of VSD or not: the VSD group (n=20) and the control group (n=18). The following parameters were used to evaluate the healing process: changes in the mean areas of the ulcers; healing rate (HR); epithelial hyperplasia and angiogenesis as determined by hematoxylin-eosin staining (HE staining); and expression of CD34, CD68 and VEGF as assessed through immunohistochemistry. Perioperative side effects and complications were also recorded.
resultsAll patients received follow-up and eventually healed. The mean area of wounds was reduced in the VSD group compared to the control group (1.75±0.64 cm
conclusionVSD could significantly accelerate the wound healing process, probably by enhancing the inflammatory response and promoting granulation and angiogenesis in DFUs.
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