ArticleNeuropsychiatric disease and treatment2021
The Health-Related Quality of Life, Work Productivity, Healthcare Resource Utilization, and Economic Burden Associated with Levels of Suicidal Ideation Among Patients Self-Reporting Moderately Severe or Severe Major Depressive Disorder in a National Survey.
Article in Neuropsychiatric disease and treatment, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 33 citations in OpenAlex.
- Enhancing group lifestyle intervention for depression with ecological momentary assessment: a pilot randomized controlled trial.Scientific reports · 2025Trial
- Treatments for Individuals with Suicidal Thoughts: Use, Indications, and Helpfulness.Journal of affective disorders reports · 2026Article
- Colorectal Cancer and the Risk of Mortality Among Individuals with Suicidal Ideation.International journal of environmental research and public health · 2025Article
- Article
- Evidence of higher suicidal ideation among young adults in Canada during the COVID-19 pandemic.Scientific reports · 2024Article
- Real-world evidence from a retrospective study on suicide during depression: clinical characteristics, treatment patterns and disease burden.BMC psychiatry · 2024Article
- Neurocognitive Remediation Therapy: A Promising Approach to Enhance Cognition in Community Living Pilots with Depression and Anxiety.Psychology research and behavior management · 2024Review
- Early Risk Factors for Self-Injurious Thoughts and Behaviours: A UK Population-Based Study of 219,581 People.Behavioral sciences (Basel, Switzerland) · 2023Article
- Effects of esketamine on patient-reported outcomes in major depressive disorder with active suicidal ideation and intent: a pooled analysis of two randomized phase 3 trials (ASPIRE I and ASPIRE II).Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Article
- Self-reported suicidal behaviours and associated factors in the general population of Latvia (2010-2018).The International journal of social psychiatry · 2023Article
- Differences in quality-of-life scores across injury categories by mental health status among injured U.S. military service members and veterans.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Article
- The Burden of Attention-Deficit/Hyperactivity Disorder Traits in Adult Patients with Major Depressive Disorder in Japan.Neuropsychiatric disease and treatment · 2023Article
- Association of chronic diseases and lifestyle factors with suicidal ideation among adults aged 18-69 years in Eswatini: evidence from a population-based survey.BMC public health · 2021Article
- Treatment patterns of patients diagnosed with major depressive disorder and suicidal ideation or attempt: a U.S. population-based study utilizing real-world data.BMC psychiatry · 2021Article
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSuicidal ideation (SI) is a cardinal aspect of major depressive disorder (MDD); however, patient-reported outcomes data from large-scale surveys are limited concerning SI in the context of MDD. This study aims to understand the association between varying levels of SI and health-related quality of life (HRQoL), work productivity, healthcare resource utilization (HRU), and associated costs in patients with moderately severe/severe MDD.
methodsThis was a retrospective, cross-sectional analysis of 2013 national survey data. Patients who self-reported moderately severe or severe MDD and completed the Short Form Survey Version 2 (SF-36v2), Work Productivity Loss and Activity Impairment questionnaire (WPAI), and questions related to HRU were analyzed. Direct and indirect costs were calculated. Patients were categorized and analyzed by the level of SI (no SI, low, moderate, and high) based on their response to Item 9 of the Patient Health Questionnaire-9.
resultsAmong 75,000 respondents, 15.3% self-reported receiving a physician diagnosis of moderately severe or severe MDD and 2.8% of the total sample endorsed some level of SI. Patients with high SI showed a higher burden than patients with no SI, reporting lower mean SF-36v2 mental component summary scores (
conclusionHigher levels of SI were associated with lower HRQoL, greater HRU, and more work impairment resulting in higher direct and indirect costs compared with patients with MDD but no SI. These results highlight the need to implement effective treatment models and interventions in the employed population.
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