Evidence map›Paper›PMID 33500533›Full record

SynthesisScientific reports2021

Efficacy of hyperbaric oxygen therapy for diabetic foot ulcer, a systematic review and meta-analysis of controlled clinical trials.

Rakesh Sharma, Suresh K Sharma, Shiv Kumar Mudgal, Prasuna Jelly, Kalpana Thakur

Open access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 8 pooled it
10.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 8 syntheses or guidelines pooled it, 114 citations in OpenAlex.

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  5. Guideline
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  7. Adjunctive hyperbaric oxygen therapy in the management of severe lower limb soft tissue injuries: a systematic review.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
    Pooled it
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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Rakesh SharmaCollege of Nursing, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Suresh K SharmaCollege of Nursing, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Shiv Kumar MudgalAkal College of Nursing, Eternal University, Baru Sahib, Himachal Pradesh, India.
Prasuna JellyCollege of Nursing, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India. prasunajelly@gmail.com.
Kalpana ThakurCollege of Nursing, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
All India Institute of Medical Sciences RishikeshEternal University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Studies have suggested that hyperbaric oxygen therapy (HBOT) is effective in the healing of diabetic foot ulcer (DFU); however, there is a lack of consensus. Therefore, to assess the efficacy of HBOT on diabetic foot ulcer among diabetic patients, controlled clinical trials were searched through PubMed, EMBASE, Clinical key, Ovid Discovery, ERMED, Clinical Trials.gov databases for randomized controlled trials (RCTs) and other sources until 15 September 2020. Studies that evaluated the effect of HBOT on diabetic foot ulcer, complete healing, amputation, adverse events, ulcer reduction area, and mortality rate were included. Of 1984 study records screened, 14 studies (768 participants) including twelve RCTs, and two CCTs were included as per inclusion criteria. The results with pooled analysis have shown that HBOT was significantly effective in complete healing of diabetic foot ulcer (OR = 0.29; 95% CI 0.14-0.61; I

Indexed as

Controlled Clinical Trials as TopicHyperbaric OxygenationAmputation, SurgicalDiabetic FootHumansPublication BiasRiskTreatment OutcomeWound Healing

Identifiers

PMID33500533
PMCPMC7838311
OpenAlexW3125508869

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.