Evidence map›Paper›PMID 33500505›Full record

Trial reportScientific reports2021

Subthreshold laser treatment for reticular pseudodrusen secondary to age-related macular degeneration.

Giuseppe Querques, Riccardo Sacconi, Francesco Gelormini, Enrico Borrelli, Francesco Prascina, Ilaria Zucchiatti, Lea Querques, Francesco Bandello

Registry-linked trialOpen access · goldAbstract readClinical Trial
In one paragraph

Trial report in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04847635 (Subthreshold Laser Treatment for Reticular Pseudodrusen Secondary to Age-related Macular Degeneration), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04847635 narecruitingnot on this map

Subthreshold Laser Treatment for Reticular Pseudodrusen Secondary to Age-related Macular Degeneration

TypeinterventionalSponsorOspedale San RaffaeleRan2021 to 2026Enrolled50ConditionsMacular Degeneration, Senile, Laser Burn of Retina, Macular Degeneration Intermediate, Macular Degeneration, DryArmsPascal Synthesis 577 sub-threshold laser (Topcon Corporation, Tokyo, Japan), Pascal Synthesis 577 sham (Topcon Corporation, Tokyo, Japan)
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Subthreshold laser treatment in retinal diseases: a mini review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Review
  7. Review
  8. Review
  9. Review
  10. Observational
  11. Article
  12. Subretinal drusenoid deposits: An update.Taiwan journal of ophthalmology
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Giuseppe Querques *School of Medicine, Vita-Salute San Raffaele University, Milan, Italy. querques.giuseppe@hsr.it.
Riccardo Sacconi *School of Medicine, Vita-Salute San Raffaele University, Milan, Italy.
Francesco GelorminiSchool of Medicine, Vita-Salute San Raffaele University, Milan, Italy.
Enrico BorrelliSchool of Medicine, Vita-Salute San Raffaele University, Milan, Italy.
Francesco PrascinaDivision of Head and Neck, Ophthalmology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Ilaria ZucchiattiDivision of Head and Neck, Ophthalmology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Lea QuerquesDivision of Head and Neck, Ophthalmology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Francesco BandelloSchool of Medicine, Vita-Salute San Raffaele University, Milan, Italy.
Vita-Salute San Raffaele University · ITIstituto di Ricovero e Cura a Carattere Scientifico San Raffaele

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a lack of treatment aimed at the regression of reticular pseudodrusen (RPD) secondary to age-related macular degeneration (AMD). The aim of this prospective, pilot study is to evaluate the safety and short-term efficacy of subthreshold laser treatment (SLT) in patients affected by RPD secondary to dry AMD (dAMD). Twenty eyes of 20 patients (mean age 78.4 ± 6.8 years) with RPD secondary to dAMD were prospectively enrolled. All patients were treated in an extrafoveal area of 1.27 mm

Indexed as

Laser TherapyAgedAged, 80 and overFemaleFollow-Up StudiesHumansMacular DegenerationMaleRetinal DrusenTomography, Optical CoherenceVisual Field Tests

Identifiers

PMID33500505
PMCPMC7838261
OpenAlexW3125439255

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.