Evidence map›Paper›PMID 33500350›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Tissue-specific dynamic codon redefinition in

Andrew M Hudson, Nicholas L Szabo, Gary Loughran, Norma M Wills, John F Atkins, Lynn Cooley

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Regulatory landscape of widespread stop codon readthrough inbioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Ribosome biogenesis and function in development and disease.Development (Cambridge, England) · 2023
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Andrew M HudsonDepartment of Genetics, Yale School of Medicine, New Haven, CT 06520.ORCID 0000-0002-2880-2051
Nicholas L SzaboDepartment of Genetics, Yale School of Medicine, New Haven, CT 06520.ORCID 0000-0002-5055-308X
Gary LoughranSchools of Biochemistry and Microbiology, University College Cork, Cork, Ireland T12 XF62.ORCID 0000-0002-2683-5597
Norma M WillsDepartment of Human Genetics, University of Utah, Salt Lake City, UT 84112.ORCID 0000-0002-4041-9397
John F AtkinsSchools of Biochemistry and Microbiology, University College Cork, Cork, Ireland T12 XF62; j.atkins@ucc.ie lynn.cooley@yale.edu.ORCID 0000-0001-7933-0165
Lynn CooleyDepartment of Genetics, Yale School of Medicine, New Haven, CT 06520; j.atkins@ucc.ie lynn.cooley@yale.edu.ORCID 0000-0003-4665-1258
Yale University · USUniversity of Utah · USUniversity College Cork · IE

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
OOCYTE DEVELOPMENT IN DROSOPHILAR01GM043301 · NIGMS · YALE UNIVERSITY · PI COOLEY, LYNN · 1990 to 2020
$10.7M
Noncanonical regulatory mechanisms in cell biologyR35GM141961 · NIGMS · YALE UNIVERSITY · PI COOLEY, LYNN · 2021 to 2025
$3.0M
NIGMS NIH HHS R01 GM043301NIGMS NIH HHS R35 GM141961NIH HHS P40 OD018537
6 · The paper itself

Abstract

Translational stop codon readthrough occurs in organisms ranging from viruses to mammals and is especially prevalent in decoding

Indexed as

AnimalsCentral Nervous SystemCodonDNA, ComplementaryDrosophila melanogasterDrosophila ProteinsGenes, ReporterHEK293 CellsHumansImaginal DiscsMicrofilament ProteinsNeuronsOrgan SpecificityRNA, MessengerCodonDNA, ComplementaryDrosophila Proteinskel protein, DrosophilaMicrofilament ProteinsRNA, Messengercentral nervous system (CNS)DrosophilaKelchrecodingstop codon readthrough

Identifiers

PMID33500350
PMCPMC7865143
OpenAlexW3124024650

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.