ArticleAnimal microbiome2021
Differential response of digesta- and mucosa-associated intestinal microbiota to dietary insect meal during the seawater phase of Atlantic salmon.
Article in Animal microbiome, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
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Who cites it
51 citing papers in PubMed, 129 citations in OpenAlex.
- Iron nutrition and host microbiota regulation in turbot (Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Article
- Ecological dynamics of the Atlantic salmon gut microbiota across developmental phases and geographic regions.Communications biology · 2026Article
- Symbiotic bacteria may support calcium carbonate precipitation in the Gulf toadfish.PLoS biology · 2026Article
- Article
- Genotypic characterization of gut isolates from Atlantic salmon fry reveals beneficial microbes with biotechnological potential.Applied and environmental microbiology · 2026Article
- Intestinal morphology and host‑ and system‑associated microbiome dynamics during short‑term fasting and refeeding of Atlantic salmon in recirculating aquaculture systems.Scientific reports · 2026Article
- A Dangerous Prey Fish?Ecology and evolution · 2026Article
- Disordered colonic microbiota as a potential contributor to inflammation in diarrheal Jinhua weaned piglets.Animal microbiome · 2026Article
- Assessment of the effectiveness of host depletion techniques for profiling fish skin microbiomes and metagenomic analysis.Microbiology spectrum · 2026Article
- Species- and Level-Dependent Modulation of Growth and Skin and Intestinal Mucosal Microbiota in Rainbow Trout Fed Mushroom Stem Meals.Aquaculture nutrition · 2026Article
- Effects of defatted black soldier fly larvae meal on growth, nutrient digestibility, hepatopancreas biochemistry, intestinal microbiota, and phosphorus discharge of giant freshwater prawn (Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2025Article
- Unlocking microbiota potential: the role of organic copper in enhancing healthy white shrimp (Penaeus vannamei) farming.Animal microbiome · 2025Article
- Effects of Short-Term Feeding with Diets Containing Insect Meal on the Gut Microbiota of African Catfish Hybrids.Animals : an open access journal from MDPI · 2025Article
- Characterization of bacteria colonizing the mucosal layer of the gastrointestinal tract of Atlantic salmon farmed in a warm water region.Frontiers in microbiology · 2025Article
- Longitudinal study on the effects of a synbiotic supplement to Atlantic salmon diets on performance, gut microbiota and immune responses during antibiotic treatment and subsequent recovery.Animal microbiome · 2024Article
- Genomic and functional characterization of the Atlantic salmon gut microbiome in relation to nutrition and health.Nature microbiology · 2024Article
- Modulation of gut microbiota composition and predicted metabolic capacity after nutritional programming with a plant-rich diet in Atlantic salmon (Salmo salar): insights across developmental stages.Animal microbiome · 2024Article
- The impact of diets containing Hermetia illucens meal on the growth, intestinal health, and microbiota of gilthead seabream (Sparus aurata).Fish physiology and biochemistry · 2024Article
- Host evolution shapes gut microbiome composition inEcology and evolution · 2024Article
- Host-gut microbiota interactions shape parasite infections in farmed Atlantic salmon.mSystems · 2024Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundIntestinal digesta is commonly used for studying responses of microbiota to dietary shifts, yet evidence is accumulating that it represents an incomplete view of the intestinal microbiota. The present work aims to investigate the differences between digesta- and mucosa-associated intestinal microbiota in Atlantic salmon (Salmo salar) and how they may respond differently to dietary perturbations. In a 16-week seawater feeding trial, Atlantic salmon were fed either a commercially-relevant reference diet or an insect meal diet containing ~ 15% black soldier fly (Hermetia illucens) larvae meal. The digesta- and mucosa-associated distal intestinal microbiota were profiled by 16S rRNA gene sequencing.
resultsRegardless of diet, we observed substantial differences between digesta- and mucosa-associated intestinal microbiota. Microbial richness and diversity were much higher in the digesta than the mucosa. The insect meal diet altered the distal intestinal microbiota resulting in higher microbial richness and diversity. The diet effect, however, depended on the sample origin. Digesta-associated intestinal microbiota showed more pronounced changes than the mucosa-associated microbiota. Multivariate association analyses identified two mucosa-enriched taxa, Brevinema andersonii and Spirochaetaceae, associated with the expression of genes related to immune responses and barrier function in the distal intestine, respectively.
conclusionsOur data show that salmon intestinal digesta and mucosa harbor microbial communities with clear differences. While feeding insects increased microbial richness and diversity in both digesta- and mucosa-associated intestinal microbiota, mucosa-associated intestinal microbiota seems more resilient to variations in the diet composition. To fully unveil the response of intestinal microbiota to dietary changes, concurrent profiling of digesta- and mucosa-associated intestinal microbiota is recommended whenever feasible. Specific taxa enriched in the intestinal mucosa are associated to gene expression related to immune responses and barrier function. Detailed studies are needed on the ecological and functional significance of taxa associated to intestinal microbiota dwelling on the mucosa.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.