ArticleBMC pediatrics2021
Annual trend of neonatal mortality and its underlying causes: population-based study - São Paulo State, Brazil, 2004-2013.
Article in BMC pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Development and validation of an epidemiological risk score for neonatal death in a middle-income country.Frontiers in public health · 2025Article
- Spatial variations and predictors of neonatal mortality among births to HIV-infected and non-infected mothers in rural Zambia.PLOS global public health · 2025Article
- Analysis of Risk Determinants of Neonatal Mortality in the Last Decade: A Systematic Literature Review (2013-2023).Pediatric reports · 2024Review
- Temporal Trend and Risk Factors for Respiratory Distress Syndrome-Associated Neonatal Mortality in Preterm Infants: A Population-Based Study in a Middle-Income Country.American journal of perinatology · 2024Article
- Temporal Trend, Causes, and Timing of Neonatal Mortality of Moderate and Late Preterm Infants in São Paulo State, Brazil: A Population-Based Study.Children (Basel, Switzerland) · 2023Article
- The burden of inappropriate birth weight on neonatal survival in term newborns: a population-based study in a middle-income setting.Frontiers in pediatrics · 2023Article
- Infant Mortality in a Brazilian Municipality with a High Human Development Index.Turkish archives of pediatrics · 2022Article
- Crossing birth and mortality data as a clue for prevalence of congenital diaphragmatic hernia in Sao Paulo State: A cross sectional study.Lancet regional health. Americas · 2022Article
- Factors associated with 5-min APGAR score, death and survival in neonatal intensive care: a case-control study.BMC pediatrics · 2022Article
- Are Primary Health Care Features Associated with Reduced Late Neonatal Mortality in Brazil? An Ecological Study.Maternal and child health journal · 2022Article
- Neonatal Mortality Rate and Its Determinants: A Community-Based Panel Study in Ethiopia.Frontiers in pediatrics · 2022Article
- Neonatal mortality associated with perinatal asphyxia: a population-based study in a middle-income country.BMC pregnancy and childbirth · 2021Article
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16 authors.
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Abstract
backgroundPopulation-based studies analyzing neonatal deaths in middle-income countries may contribute to design interventions to achieve the Sustainable Development Goals, established by United Nations. This study goal is to analyze the annual trend of neonatal mortality in São Paulo State, Brazil, over a 10-year period and its underlying causes and to identify maternal and neonatal characteristics at birth associated with neonatal mortality.
methodA population-based study of births and deaths from 0 to 27 days between 2004 and 2013 in São Paulo State, Brazil, was performed. The annual trend of neonatal mortality rate according to gestational age was analyzed by Poisson or by Negative Binomial Regression models. Basic causes of neonatal death were classified according to ICD-10. Association of maternal demographic variables (block 1), prenatal and delivery care variables (block 2), and neonatal characteristics at birth (block 3) with neonatal mortality was evaluated by Poisson regression analysis adjusted by year of birth.
resultsAmong 6,056,883 live births in São Paulo State during the study period, 48,309 died from 0 to 27 days (neonatal mortality rate: 8.0/1,000 live births). For the whole group and for infants with gestational age 22-27, 28-31, 32-36, 37-41 and ≥ 42 weeks, reduction of neonatal mortality rate was, respectively, 18 %, 15 %, 38 %, 53 %, 31 %, and 58 %. Median time until 50 % of deaths occurred was 3 days. Main basic causes of death were respiratory disorders (25 %), malformations (20 %), infections (17 %), and perinatal asphyxia (7 %). Variables independently associated with neonatal deaths were maternal schooling, prenatal care, parity, newborn sex, 1st minute Apgar, and malformations. Cesarean delivery, compared to vaginal, was protective against neonatal mortality for infants at 22-31 weeks, but it was a risk factor for those with 32-41 weeks.
conclusionsDespite the significant decrease in neonatal mortality rate over the 10-year period in São Paulo State, improved access to qualified health care is needed in order to avoid preventable neonatal deaths and increase survival of infants that need more complex levels of assistance.
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