Evidence map›Paper›PMID 33499376›Full record

Trial reportNutrients2021

Effects of Randomized Controlled Infancy-Onset Dietary Intervention on Leukocyte Telomere Length-The Special Turku Coronary Risk Factor Intervention Project (STRIP).

Niina Pitkänen, Katja Pahkala, Suvi P Rovio, Outi J Saijonmaa, Anna E Nyman, Antti Jula, Hanna Lagström, Jorma S A Viikari, Tapani Rönnemaa, Harri Niinikoski and 3 more

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Niina PitkänenResearch Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, 20520 Turku, Finland.
Katja PahkalaResearch Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, 20520 Turku, Finland.ORCID 0000-0001-9338-4397
Suvi P RovioResearch Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, 20520 Turku, Finland.ORCID 0000-0003-0911-7478
Outi J SaijonmaaMinerva Institute for Medical Research, 00290 Helsinki, Finland.
Anna E NymanMinerva Institute for Medical Research, 00290 Helsinki, Finland.
Antti JulaDepartment of Public Health Solutions, Institute for Health and Welfare, 20750 Turku, Finland.
Hanna LagströmCentre for Population Health Research, University of Turku and Turku University Hospital, 20520 Turku, Finland.ORCID 0000-0002-5069-6582
Jorma S A ViikariDepartment of Medicine, University of Turku, 20520 Turku, Finland.
Tapani RönnemaaDepartment of Medicine, University of Turku, 20520 Turku, Finland.
Harri NiinikoskiCentre for Population Health Research, University of Turku and Turku University Hospital, 20520 Turku, Finland.ORCID 0000-0002-7071-918X
Olli SimellResearch Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, 20520 Turku, Finland.
Frej FyhrquistMinerva Institute for Medical Research, 00290 Helsinki, Finland.
Olli T RaitakariResearch Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, 20520 Turku, Finland.
University of Turku · FIMinerva Foundation · FIFinnish Institute for Health and Welfare · FI

Funding

Academy of Finland 206374, 294834, 251360, 275595, 307996, 322112Juho Vainion Säätiö NAOpetus- ja Kulttuuriministeriö NASigrid Juséliuksen Säätiö NASpecial Governmental grants for Health Sciences Research (Turku University Hospital) NASuomen Kulttuurirahasto NASuomen Lääketieteen Säätiö NASydäntutkimussäätiö NATurku University Foundation NAYrjö Jahnssonin Säätiö NA
6 · The paper itself

Abstract

Reduced telomere length (TL) is a biological marker of aging. A high inter-individual variation in TL exists already in childhood, which is partly explained by genetics, but also by lifestyle factors. We examined the influence of a 20-year dietary/lifestyle intervention on TL attrition from childhood to early adulthood. The study comprised participants of the longitudinal randomized Special Turku Coronary Risk Factor Intervention Project (STRIP) conducted between 1990 and 2011. Healthy 7-month-old children were randomized to the intervention group (

Indexed as

AdolescentBlood PressureCardiometabolic Risk FactorsChildChild, PreschoolDietary FatsDiet, Fat-RestrictedExerciseFemaleFinlandHumansInfantInsulinLife StyleMaleProspective StudiesDietary FatsInsulinchildhooddietary interventiongeneticsrisk factorstelomere attritiontelomere length

Identifiers

PMID33499376
PMCPMC7911579
OpenAlexW3123011995

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.