Evidence map›Paper›PMID 33499347›Full record

ArticleInternational journal of environmental research and public health2021

Impact of a Gender-Neutral HPV Vaccination Program in Men Who Have Sex with Men (MSM).

Javier Díez-Domingo, Víctor Sánchez-Alonso, Rafael-J Villanueva, Luis Acedo, José Tuells

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Prevalence of anal infection by human papillomavirus in men who have sex with men and its associated clinical and epidemiological factors.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2025
    Article
  5. Article
  6. Factors Related to HPV Vaccination Intention among MSM in China: A Bayesian Network Model.International journal of environmental research and public health · 2022
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Javier Díez-DomingoVaccine Research Area, FISABIO-Public Health, Avda. Cataluña, 21, 46020 Valencia, Spain.
Víctor Sánchez-AlonsoInstituto Universitario de Matemática Multidisciplinar, 8G building, 2nd Floor, Camino de Vera, Universitat Politècnica de Valéncia, 46022 Valencia, Spain.
Rafael-J VillanuevaInstituto Universitario de Matemática Multidisciplinar, 8G building, 2nd Floor, Camino de Vera, Universitat Politècnica de Valéncia, 46022 Valencia, Spain.ORCID 0000-0002-0131-0532
Luis AcedoDepartment Mathematics, University of Extremadura (Centro Universitario de Plasencia), 10600 Plasencia, Spain.ORCID 0000-0002-9118-1200
José TuellsDepartment of Community Nursing, Preventive Medicine and Public Health and History of Science, University of Alicante, San Vicente del Raspeig, 03690 Alicante, Spain.ORCID 0000-0003-1159-429X
Universitat Politècnica de València · ESFundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana · ESUniversidad de Extremadura · ESUniversity of Alicante · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A major challenge in human papillomavirus (HPV) vaccine programs is the universal gender-neutral recommendation, as well as estimation of its long-term effect. The objective of this study is to predict the added benefit of male vaccination, especially in men who have sex with men (MSM), and to analyze the impact of the program on society. We propose a mathematical model of the HPV infection based on a network paradigm. Data from Spain allowed constructing the sexual network. HPV force of infection was taken from literature. Different scenarios using variable vaccine coverage in both males and females were studied. Strong herd immunity is shown in the heterosexual population, with an important decrease of HPV 6/11 infections both in men and in unvaccinated women with an only-women vaccination at 14 years of age. No impact of this program occurred in the infection incidence in MSM. This group would only benefit from a vaccination program that includes males. However, the impact at short term would be lower than in heterosexual men. The protection of MSM can only be achieved by direct vaccination of males. This may have important consequences for public health.

Indexed as

Papillomavirus InfectionsPapillomavirus VaccinesSexual and Gender MinoritiesFemaleHomosexuality, MaleHumansMaleSpainVaccinationPapillomavirus Vaccinesepidemiologic transitionhuman papillomavirusmen who have sex with mennetwork modelsexual behaviorsexual partnersvaccination strategies

Identifiers

PMID33499347
PMCPMC7908442
OpenAlexW3122878993

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.