Evidence map›Paper›PMID 33499342›Full record

ArticleMolecules (Basel, Switzerland)2021

Carboxymethyl Cellulose Entrapped in a Poly(vinyl) Alcohol Network: Plant-Based Scaffolds for Cartilage Tissue Engineering.

Jirapat Namkaew, Panitporn Laowpanitchakorn, Nuttapong Sawaddee, Sirinee Jirajessada, Sittisak Honsawek, Supansa Yodmuang

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
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  7. Review
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  10. Review
  11. Nanocellulose-Based Scaffolds for Chondrogenic Differentiation and Expansion.Frontiers in bioengineering and biotechnology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jirapat NamkaewExcellence Center for Advanced Therapy Medicinal Products, King Chulalongkorn Memorial Hospital, Pathumwan, Bangkok 10330, Thailand.
Panitporn LaowpanitchakornBiomaterial Engineering for Medical and Health Research Unit, Chulalongkorn University, Pathumwan, Bangkok 10330, Thailand.
Nuttapong SawaddeeExcellence Center for Advanced Therapy Medicinal Products, King Chulalongkorn Memorial Hospital, Pathumwan, Bangkok 10330, Thailand.
Sirinee JirajessadaBiology Program, Faculty of Science, Buriram Rajabhat University, Muang, Buriram 31000, Thailand.
Sittisak HonsawekOsteoarthritis and Musculoskeleton Research Unit, Faculty of Medicine, Chulalongkorn University, Pathumwan, Bangkok 10330, Thailand.ORCID 0000-0003-3852-9092
Supansa YodmuangResearch Affairs, Faculty of Medicine, Chulalongkorn University, Pathumwan, Bangkok 10330, Thailand.ORCID 0000-0002-4305-3212
Chulalongkorn University · THKing Chulalongkorn Memorial Hospital · THBuriram Rajabhat University · TH

Funding

Ratchadapiseksompotch Fund, Faculty of Medicine, Chulalongkorn University RA60/116Thailand Research Fund MRG6080058
6 · The paper itself

Abstract

Cartilage has a limited inherent healing capacity after injury, due to a lack of direct blood supply and low cell density. Tissue engineering in conjunction with biomaterials holds promise for generating cartilage substitutes that withstand stress in joints. A major challenge of tissue substitution is creating a functional framework to support cartilage tissue formation. Polyvinyl alcohol (PVA) was crosslinked with glutaraldehyde (GA), by varying the mole ratios of GA/PVA in the presence of different amounts of plant-derived carboxymethyl cellulose (CMC). Porous scaffolds were created by the freeze-drying technique. The goal of this study was to investigate how CMC incorporation and crosslinking density might affect scaffold pore formation, swelling behaviors, mechanical properties, and potential use for engineered cartilage. The peak at 1599 cm

Indexed as

Biocompatible MaterialsCalorimetry, Differential ScanningCarboxymethylcellulose SodiumCartilage, ArticularCell AdhesionCells, CulturedCell SurvivalChondrocytesCross-Linking ReagentsElastic ModulusHumansHydrogelsMaterials TestingMicroscopy, Electron, ScanningPolyvinyl AlcoholPorosityBiocompatible MaterialsCarboxymethylcellulose SodiumCross-Linking ReagentsHydrogelsPolyvinyl Alcoholpoly(vinyl) alcoholscaffoldssodium carboxymethyl cellulosetissue engineering

Identifiers

PMID33499342
PMCPMC7865723
OpenAlexW3124370314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.