Evidence map›Paper›PMID 33499329›Full record

ArticleAntioxidants (Basel, Switzerland)2021

Reevaluation of Serum Arylesterase Activity in Neurodevelopmental Disorders.

Ignazio Stefano Piras, Stefano Gabriele, Laura Altieri, Federica Lombardi, Roberto Sacco, Carla Lintas, Barbara Manzi, Paolo Curatolo, Maria Nobile, Catia Rigoletto and 2 more

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Ignazio Stefano PirasUnit of Child & Adolescent Neuropsychiatry, University Campus Bio-Medico, I-00128 Rome, Italy.
Stefano GabrieleUnit of Child & Adolescent Neuropsychiatry, University Campus Bio-Medico, I-00128 Rome, Italy.
Laura AltieriUnit of Child & Adolescent Neuropsychiatry, University Campus Bio-Medico, I-00128 Rome, Italy.
Federica LombardiUnit of Child & Adolescent Neuropsychiatry, University Campus Bio-Medico, I-00128 Rome, Italy.
Roberto SaccoUnit of Child & Adolescent Neuropsychiatry, University Campus Bio-Medico, I-00128 Rome, Italy.
Carla LintasUnit of Child & Adolescent Neuropsychiatry, University Campus Bio-Medico, I-00128 Rome, Italy.ORCID 0000-0003-1209-8554
Barbara ManziUnit of Child and Adolescent Neuropsychiatry, University of Rome "Tor Vergata", I-00133 Rome, Italy.
Paolo CuratoloUnit of Child and Adolescent Neuropsychiatry, University of Rome "Tor Vergata", I-00133 Rome, Italy.
Maria NobileChild Psychopathology Unit, Scientific Institute, IRCCS 'E. Medea', I-23842 Bosisio Parini (LC), Italy.
Catia RigolettoChild Psychopathology Unit, Scientific Institute, IRCCS 'E. Medea', I-23842 Bosisio Parini (LC), Italy.
Massimo MolteniChild Psychopathology Unit, Scientific Institute, IRCCS 'E. Medea', I-23842 Bosisio Parini (LC), Italy.
Antonio M PersicoInterdepartmental Program "Autism 0-90", "G. Martino" University Hospital, University of Messina, I-98122 Messina, Italy.
Università Campus Bio-Medico · ITIRCCS Eugenio Medea · ITUniversity of Rome Tor Vergata · ITTranslational Genomics Research Institute · USUniversity of Messina · IT

Funding

Ministero della Salute RFPS-2007-5-640174Ministero dell'Istruzione, dell'Università e della Ricerca Prin n2006058195Ministero dell'Istruzione, dell'Università e della Ricerca Prin n. 2008BACT54_002
6 · The paper itself

Abstract

Organophosphate compounds (OPs) interfere with neurodevelopment and are neurotoxic for humans and animals. They are first biotransformed to the more toxic oxon form, and then hydrolyzed to specific metabolites by the enzyme paraoxonase/arylesterase, encoded by the gene

Indexed as

arylesteraseattention deficit/hyperactivity disorder (ADHD)autismautism spectrum disorderdevelopmental language disorderorganophosphateparoxonasepesticidespecific language impairment

Identifiers

PMID33499329
PMCPMC7912005
OpenAlexW3122593527

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.