Evidence map›Paper›PMID 33499154›Full record

ArticleGenes2021

Identification of Variants (rs11571707, rs144848, and rs11571769) in the

Elizabeth Ayres Fragoso Dobbin, Jéssyca Amanda Gomes Medeiros, Marta Solange Camarinha Ramos Costa, Juliana Carla Gomes Rodrigues, João Farias Guerreiro, José Eduardo Kroll, Sandro José de Souza, Paulo Pimentel de Assumpção, Ândrea Ribeiro-Dos-Santos, Sidney Emanuel Batista Dos Santos and 3 more

Open access · goldAbstract read
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Epidemiological profile of breast cancer in a reference center in the north region of Brazil.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025
    Article
  5. Association of Gene Polymorphisms with Breast Cancer Risk in the Kazakh Population.Asian Pacific journal of cancer prevention : APJCP · 2023
    Article
  6. Variants ofGenes · 2023
    Article
  7. Article
  8. Pharmacogenomic Profile of Amazonian Amerindians.Journal of personalized medicine · 2022
    Article
  9. Article
  10. Characterization ofGenes · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Elizabeth Ayres Fragoso DobbinNúcleo de Pesquisas em Oncologia, Universidade Federal do Pará, Belém 66075-110, Brazil.ORCID 0000-0003-3289-390X
Jéssyca Amanda Gomes MedeirosNúcleo de Pesquisas em Oncologia, Universidade Federal do Pará, Belém 66075-110, Brazil.ORCID 0000-0003-1838-5298
Marta Solange Camarinha Ramos CostaNúcleo de Pesquisas em Oncologia, Universidade Federal do Pará, Belém 66075-110, Brazil.
Juliana Carla Gomes RodriguesNúcleo de Pesquisas em Oncologia, Universidade Federal do Pará, Belém 66075-110, Brazil.ORCID 0000-0003-1665-3535
João Farias GuerreiroLaboratório de Genética Humana e Médica, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 66075-110, Brazil.ORCID 0000-0003-1979-3656
José Eduardo KrollBrain Institute, Universidade Federal do Rio Grande do Norte, Natal 59078-970, Brazil.ORCID 0000-0002-7657-9536
Sandro José de SouzaBrain Institute, Universidade Federal do Rio Grande do Norte, Natal 59078-970, Brazil.
Paulo Pimentel de AssumpçãoNúcleo de Pesquisas em Oncologia, Universidade Federal do Pará, Belém 66075-110, Brazil.
Ândrea Ribeiro-Dos-SantosNúcleo de Pesquisas em Oncologia, Universidade Federal do Pará, Belém 66075-110, Brazil.ORCID 0000-0001-7001-1483
Sidney Emanuel Batista Dos SantosNúcleo de Pesquisas em Oncologia, Universidade Federal do Pará, Belém 66075-110, Brazil.
Rommel Mario Rodríguez BurbanoNúcleo de Pesquisas em Oncologia, Universidade Federal do Pará, Belém 66075-110, Brazil.
Marianne Rodrigues FernandesNúcleo de Pesquisas em Oncologia, Universidade Federal do Pará, Belém 66075-110, Brazil.
Ney Pereira Carneiro Dos SantosNúcleo de Pesquisas em Oncologia, Universidade Federal do Pará, Belém 66075-110, Brazil.
Universidade Federal do Pará · BRUniversidade Federal do Rio Grande do Norte · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Estimates show that 5-10% of breast cancer cases are hereditary, caused by genetic variants in autosomal dominant genes; of these, 16% are due to germline mutations in the

Indexed as

AllelesMutationBrazilBRCA1 ProteinBRCA2 ProteinBreast NeoplasmsGene FrequencyGenetic Predisposition to DiseaseGenotypeGerm-Line MutationHumansPopulation GroupsBRCA1 ProteinBRCA1 protein, humanBRCA2 ProteinBRCA2 protein, humanBrazilBRCA1BRCA2hereditary breast cancerindigenous populationsNative Americans

Identifiers

PMID33499154
PMCPMC7911168
OpenAlexW3122223471

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.