Evidence map›Paper›PMID 33498968›Full record

ArticleChildren (Basel, Switzerland)2021

A Novel Association between YKL-40, a Marker of Structural Lung Disease, and Short Telomere Length in 10-Year-Old Children with Bronchopulmonary Dysplasia.

Ewa Henckel, Anna James, Jon R Konradsen, Björn Nordlund, Malin Kjellberg, Eva Berggren-Broström, Gunilla Hedlin, Sofie Degerman, Kajsa Bohlin

Open access · goldAbstract read
In one paragraph

Article in Children (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Moderate-to-late prematurity: understanding respiratory consequences and modifiable risk factors.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Paediatrics: messages from Munich.ERJ open research · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Ewa HenckelDepartment of Clinical Science, Intervention and Technology, Karolinska Institutet, 141 86 Stockholm, Sweden.ORCID 0000-0003-0775-1563
Anna JamesDepartment of Experimental Asthma and Allergy Research, Institute of Environmental Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden.
Jon R KonradsenDepartment of Women's and Children's Health, Karolinska Institutet, 171 77 Stockholm, Sweden.ORCID 0000-0001-7745-8624
Björn NordlundDepartment of Women's and Children's Health, Karolinska Institutet, 171 77 Stockholm, Sweden.
Malin KjellbergDepartment of Women's and Children's Health, Karolinska Institutet, 171 77 Stockholm, Sweden.
Eva Berggren-BroströmDepartment of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, 118 83 Stockholm, Sweden.
Gunilla HedlinDepartment of Women's and Children's Health, Karolinska Institutet, 171 77 Stockholm, Sweden.
Sofie DegermanDepartment of Clinical Microbiology, Umeå University, 907 36 Umeå, Sweden.ORCID 0000-0002-2783-0712
Kajsa BohlinDepartment of Clinical Science, Intervention and Technology, Karolinska Institutet, 141 86 Stockholm, Sweden.
Karolinska University Hospital · SEKarolinska Institutet · SEUmeå University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extremely preterm infants are born with immature lungs and are exposed to an inflammatory environment as a result of oxidative stress. This may lead to airway remodeling, cellular aging and the development of bronchopulmonary dysplasia (BPD). Reliable markers that predict the long-term consequences of BPD in infancy are still lacking. We analyzed two biomarkers of cellular aging and lung function, telomere length and YKL-40, respectively, at 10 years of age in children born preterm with a history of BPD (

Indexed as

biomarkerbronchopulmonary dysplasiainflammation-accelerated aginglung functionoxidative stresspretermSPECTtelomere lengthV/Q ratioYKL-40

Identifiers

PMID33498968
PMCPMC7912154
OpenAlexW3123301199

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.