Evidence map›Paper›PMID 33498917›Full record

ArticleJournal of personalized medicine2021

Potential Neurophysiological Mechanisms of 1Hz-TMS to the Right Prefrontal Cortex for Depression: An Exploratory TMS-EEG Study in Healthy Participants.

Yoshihiro Noda

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Yoshihiro NodaDepartment of Neuropsychiatry, Graduate School of Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.ORCID 0000-0002-2155-0357
Keio University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe present study aimed to examine the acute neurophysiological effects of 1Hz transcranial magnetic stimulation (TMS) administered to the right dorsolateral prefrontal cortex (DLPFC) in healthy participants.

methodsTMS combined with simultaneous electroencephalography (EEG) recording was conducted for 21 healthy participants. For the right DLPFC, 1Hz-TMS (100 pulses/block × 17 sessions) was applied in the resting-state, while for the left DLPFC, 1Hz-TMS (100 pulses/block × 2 sessions) was administered during the verbal fluency tasks (VFTs). For TMS-EEG data, independent component analysis (ICA) was applied to extract TMS-evoked EEG potentials to calculate TMS-related power as well as TMS-related coherence from the F4 and F3 electrode sites during the resting-state and VFTs.

resultsTMS-related power was significantly increased in alpha, beta, and gamma bands by 1Hz-TMS at the stimulation site during the resting-state, while TMS-related power was significantly increased in alpha and beta bands but not in the gamma band during the VFTs. On the other hand, TMS-related coherence in alpha and beta bands significantly increased but not in gamma band by 1Hz-TMS that was administered to the right DLPFC in resting-state, whereas there were no significant changes in coherence for all frequency bands by 1Hz-TMS that applied to the left DLPFC during the VFTs.

conclusionsCollectively, 1Hz-repetitive TMS (rTMS) to the right DLPFC may rapidly neuromodulate EEG activity, which might be associated with a therapeutic mechanism for depression.

Indexed as

dorsolateral prefrontal cortex (DLPFC)electroencephalography (EEG)neuromodulationneurophysiologyTMS-EEGTMS-evoked potential (TEP)TMS-related coherenceTMS-related powertranscranial magnetic stimulation (TMS)

Identifiers

PMID33498917
PMCPMC7910865
OpenAlexW3121407621

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.