Evidence map›Paper›PMID 33498793›Full record

ArticleViruses2021

HIV-1

Anne Kapaata, Sheila N Balinda, Rui Xu, Maria G Salazar, Kimberly Herard, Kelsie Brooks, Kato Laban, Jonathan Hare, Dario Dilernia, Anatoli Kamali and 8 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 4 countries.

Anne KapaataMedical Research Council, UVRI & LSTHM Uganda Research Unit, Plot 51-59, Entebbe, Uganda.
Sheila N BalindaMedical Research Council, UVRI & LSTHM Uganda Research Unit, Plot 51-59, Entebbe, Uganda.ORCID 0000-0001-8374-3122
Rui XuEmory University, Atlanta, GA 30322, USA.
Maria G SalazarMedical Research Council, UVRI & LSTHM Uganda Research Unit, Plot 51-59, Entebbe, Uganda.
Kimberly HerardEmory University, Atlanta, GA 30322, USA.
Kelsie BrooksEmory University, Atlanta, GA 30322, USA.
Kato LabanMedical Research Council, UVRI & LSTHM Uganda Research Unit, Plot 51-59, Entebbe, Uganda.
Jonathan HareImperial College London, London SW7 2AZ, UK.
Dario DilerniaEmory University, Atlanta, GA 30322, USA.
Anatoli KamaliIAVI, Nairobi 00202, Kenya.
Eugene RuzagiraMedical Research Council, UVRI & LSTHM Uganda Research Unit, Plot 51-59, Entebbe, Uganda.
Freddie MukasaMedical Research Council, UVRI & LSTHM Uganda Research Unit, Plot 51-59, Entebbe, Uganda.
Jill GilmourImperial College London, London SW7 2AZ, UK.
Jesus F Salazar-GonzalezMedical Research Council, UVRI & LSTHM Uganda Research Unit, Plot 51-59, Entebbe, Uganda.ORCID 0000-0003-4626-6448
Ling YueEmory University, Atlanta, GA 30322, USA.
Matthew CottenMedical Research Council, UVRI & LSTHM Uganda Research Unit, Plot 51-59, Entebbe, Uganda.
Eric HunterEmory University, Atlanta, GA 30322, USA.ORCID 0000-0002-4273-8631
Pontiano KaleebuMedical Research Council, UVRI & LSTHM Uganda Research Unit, Plot 51-59, Entebbe, Uganda.
Uganda Virus Research Institute · UGEmory University · USInternational AIDS Vaccine Initiative · USKenya AIDS Vaccine Initiative · KEMRC University of Glasgow Centre for Virus Research · GB

Funding

Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0M
Medical Research Council MC_EX_MR/L016273/1Medical Research Council MC_UU_00027/1NIH HHS P51 OD011132
6 · The paper itself

Abstract

The ability to efficiently establish a new infection is a critical property for human immunodeficiency virus type 1 (HIV-1). Although the envelope protein of the virus plays an essential role in receptor binding and internalization of the infecting virus, the structural proteins, the polymerase and the assembly of new virions may also play a role in establishing and spreading viral infection in a new host. We examined Ugandan viruses from newly infected patients and focused on the contribution of the

Indexed as

Virus ReplicationAdultFemalegag Gene Products, Human Immunodeficiency VirusHIV-1HIV InfectionsHIV ProteaseHumansMaleMiddle Agedpol Gene Products, Human Immunodeficiency VirusProtein DomainsUgandaYoung Adultgag Gene Products, Human Immunodeficiency VirusHIV Proteasepol Gene Products, Human Immunodeficiency VirusGag-PolHIV-1protein domainsrecombinantUganda

Identifiers

PMID33498793
PMCPMC7912664
OpenAlexW3121814992

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.