Evidence map›Paper›PMID 33498722›Full record

ArticleBiomolecules2021

Syntaxin 1A Gene Is Negatively Regulated in a Cell/Tissue Specific Manner by YY1 Transcription Factor, Which Binds to the -183 to -137 Promoter Region Together with Gene Silencing Factors Including Histone Deacetylase.

Takahiro Nakayama, Toshiyuki Fukutomi, Yasuo Terao, Kimio Akagawa

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. A Single-Nucleotide Polymorphism in the Promoter of PorcineFrontiers in cell and developmental biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Takahiro NakayamaDepartment of Medical Physiology, Kyorin University School of Medicine, Tokyo 181-8611, Japan.ORCID 0000-0003-3064-3536
Toshiyuki FukutomiDepartment of Pharmacology and Toxicology, Kyorin University School of Medicine, Tokyo 181-8611, Japan.
Yasuo TeraoDepartment of Medical Physiology, Kyorin University School of Medicine, Tokyo 181-8611, Japan.
Kimio AkagawaDepartment of Medical Physiology, Kyorin University School of Medicine, Tokyo 181-8611, Japan.
Kyorin University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The HPC-1/syntaxin 1A (

Indexed as

Gene Expression RegulationGene SilencingPromoter Regions, GeneticAnimalsCell Line, TumorChromatin ImmunoprecipitationHistone Deacetylase InhibitorsHistone DeacetylasesHydroxamic AcidsMass SpectrometryRatsRepressor ProteinsSyntaxin 1YY1 Transcription FactorHistone Deacetylase InhibitorsHistone DeacetylasesHydroxamic AcidsRepressor ProteinsStx1a protein, ratSyntaxin 1trichostatin AYy1 protein, ratYY1 Transcription Factorgene silencingheterochromatinhistone deacetylaseneurodevelopmental disordernon-neuronalSNARE

Identifiers

PMID33498722
PMCPMC7910890
OpenAlexW3123664404

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.