Evidence map›Paper›PMID 33498572›Full record

ArticleMaterials (Basel, Switzerland)2021

Chitosan-Based Biomaterial, Calcium Hydroxide and Chlorhexidine for Potential Use as Intracanal Medication.

Bruna de Siqueira Nunes, Rosana Araújo Rosendo, Abrahão Alves de Oliveira Filho, Marcus Vinícius Lia Fook, Wladymyr Jefferson Bacalhau de Sousa, Rossemberg Cardoso Barbosa, Hermano de Vasconcelos Pina, João Emídio da Silva Neto, Solomon Kweku Sagoe Amoah, Carlos Eduardo Fontana and 2 more

Abstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Antimicrobial efficacy of chitosan nanoparticles as intracanal medicament againstJournal of conservative dentistry and endodontics · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Bruna de Siqueira NunesRua Antônio Mariano de Sousa, 31, Antônio Marinho, São José do Egito 56700-000, PE, Brazil.
Rosana Araújo RosendoUnidade Acadêmica de Ciências Biológicas (UACB)-Universidade Federal de Campina Grande (UFCG), Avenida Universitária, s/n, Bairro Santa Cecília, Cx Postal 61, Patos 58708-110, PB, Brazil.
Abrahão Alves de Oliveira FilhoUnidade Acadêmica de Ciências Biológicas (UACB)-Universidade Federal de Campina Grande (UFCG), Avenida Universitária, s/n, Bairro Santa Cecília, Cx Postal 61, Patos 58708-110, PB, Brazil.
Marcus Vinícius Lia FookLaboratório de Avaliação e Desenvolvimento de Biomateriais do Nordeste-CERTBIO/UFCG, Campina Grande 58429-900, PB, Brazil.
Wladymyr Jefferson Bacalhau de SousaLaboratório de Avaliação e Desenvolvimento de Biomateriais do Nordeste-CERTBIO/UFCG, Campina Grande 58429-900, PB, Brazil.
Rossemberg Cardoso BarbosaLaboratório de Avaliação e Desenvolvimento de Biomateriais do Nordeste-CERTBIO/UFCG, Campina Grande 58429-900, PB, Brazil.
Hermano de Vasconcelos PinaLaboratório de Avaliação e Desenvolvimento de Biomateriais do Nordeste-CERTBIO/UFCG, Campina Grande 58429-900, PB, Brazil.
João Emídio da Silva NetoLaboratório de Avaliação e Desenvolvimento de Biomateriais do Nordeste-CERTBIO/UFCG, Campina Grande 58429-900, PB, Brazil.
Solomon Kweku Sagoe AmoahLaboratório de Avaliação e Desenvolvimento de Biomateriais do Nordeste-CERTBIO/UFCG, Campina Grande 58429-900, PB, Brazil.
Carlos Eduardo FontanaCentro de Ciências da Vida, Programa de Pós Graduação em Ciências da Saúde, PUC-Campinas, Av. John Boyd Dunlop, s/n, Jd. Ipaussurama, Campinas 13060-904, SP, Brazil.
Carlos Eduardo da Silveira BuenoInstituto de Pesquisas, Endodontia, São Leopoldo Mandic, Faculdade São Leopoldo Mandic, Rua Dr. José Rocha Junqueira, 13, Ponte Preta, Campinas 13045-755, SP, Brazil.
Alexandre Sigrist De MartinInstituto de Pesquisas, Endodontia, São Leopoldo Mandic, Faculdade São Leopoldo Mandic, Rua Dr. José Rocha Junqueira, 13, Ponte Preta, Campinas 13045-755, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this study was to develop a chitosan-based biomaterial with calcium hydroxide and 2% chlorhexidine for intracanal treatment application and, consequently, to diminish the number of microorganisms in the root canal system. The chitosan solution was prepared by dissolving it in 2% and 4% acetic acid (

Indexed as

biomaterialchitosanendodontics

Identifiers

PMID33498572
PMCPMC7864335

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.