Evidence map›Paper›PMID 33498495›Full record

ArticleViruses2021

A New Variant Among Newcastle Disease Viruses Isolated in the Democratic Republic of the Congo in 2018 and 2019.

Augustin T Twabela, Lam Thanh Nguyen, Justin Masumu, Patrick Mpoyo, Serge Mpiana, Julienne Sumbu, Masatoshi Okamatsu, Keita Matsuno, Norikazu Isoda, Bianca Zecchin and 2 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Molecular characterization of Newcastle disease virus obtained from Mawenzi live bird market in Morogoro, Tanzania in 2020-2021.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Augustin T TwabelaLaboratory of Microbiology, Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido 060-0818, Japan.ORCID 0000-0003-0695-2734
Lam Thanh NguyenLaboratory of Microbiology, Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido 060-0818, Japan.
Justin MasumuCentral Veterinary Laboratory of Kinshasa, Kinshasa I/Gombe 012, Democratic Republic of the Congo.
Patrick MpoyoCentral Veterinary Laboratory of Kinshasa, Kinshasa I/Gombe 012, Democratic Republic of the Congo.
Serge MpianaCentral Veterinary Laboratory of Kinshasa, Kinshasa I/Gombe 012, Democratic Republic of the Congo.
Julienne SumbuCentral Veterinary Laboratory of Kinshasa, Kinshasa I/Gombe 012, Democratic Republic of the Congo.
Masatoshi OkamatsuLaboratory of Microbiology, Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido 060-0818, Japan.
Keita MatsunoLaboratory of Microbiology, Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido 060-0818, Japan.
Norikazu IsodaLaboratory of Microbiology, Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido 060-0818, Japan.
Bianca ZecchinIstituto Zooprofilattico Sperimentale delle Venezie, 35020 Legnaro (Padova), Italy.ORCID 0000-0001-9566-6531
Isabella MonneIstituto Zooprofilattico Sperimentale delle Venezie, 35020 Legnaro (Padova), Italy.
Yoshihiro SakodaLaboratory of Microbiology, Department of Disease Control, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido 060-0818, Japan.ORCID 0000-0001-7021-1688
Hokkaido University · JPIstituto Zooprofilattico Sperimentale delle Venezie · ITCan Tho University · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Newcastle disease (ND) is a highly transmissible and devastating disease that affects poultry and wild birds worldwide. Comprehensive knowledge regarding the characteristics and epidemiological factors of the ND virus (NDV) is critical for the control and prevention of ND. Effective vaccinations can prevent and control the spread of the NDV in poultry populations. For decades, the Democratic Republic of the Congo (DRC) has reported the impacts of ND on commercial and traditional poultry farming systems. The reports were preliminary clinical observations, and few cases were confirmed in the laboratory. However, data on the phylogenetic, genetic, and virological characteristics of NDVs circulating in the DRC are not available. In this study, the whole-genome sequences of three NDV isolates obtained using the next-generation sequencing method revealed two isolates that were a new variant of NDV, and one isolate that was clustered in the subgenotype VII.2. All DRC isolates were velogenic and were antigenically closely related to the vaccine strains. Our findings reveal that despite the circulation of the new variant, ND can be controlled in the DRC using the current vaccine. However, epidemiological studies should be conducted to elucidate the endemicity of the disease so that better control strategies can be implemented.

Indexed as

AnimalsDemocratic Republic of the CongoGenotypeNewcastle DiseaseNewcastle disease virusPhylogenyPoultryPoultry DiseasesRNA, ViralViral ProteinsWhole Genome SequencingRNA, ViralViral Proteinschicken outbreakDemocratic Republic of the CongoNewcastle disease virusnew variant

Identifiers

PMID33498495
PMCPMC7909526
OpenAlexW3125484846

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.