Evidence map›Paper›PMID 33498364›Full record

ReviewInternational journal of molecular sciences2021

Selenium Compounds as Novel Potential Anticancer Agents.

Dominika Radomska, Robert Czarnomysy, Dominik Radomski, Krzysztof Bielawski

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed.

  1. NiH-Catalyzed Enantio- and Regioselective Hydroselenylation of Unactivated Alkenes.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Selenium-Containing Compounds in Breast Cancer Therapy.Biological trace element research · 2026
    Review
  7. Article
  8. Selenium-Based Nanoplatforms: An Emerging Theranostic Paradigm for Gynecological Cancers.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Synthesis of 2-Aryl-3-(organoselanyl)-4The Journal of organic chemistry · 2025
    Article
  17. Review
  18. Article
  19. Review
  20. Article

19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dominika RadomskaDepartment of Synthesis and Technology of Drugs, Medical University of Bialystok, Jana Kilinskiego 1, 15-089 Bialystok, Poland.ORCID 0000-0002-4747-0312
Robert CzarnomysyDepartment of Synthesis and Technology of Drugs, Medical University of Bialystok, Jana Kilinskiego 1, 15-089 Bialystok, Poland.ORCID 0000-0002-7148-6111
Dominik RadomskiDepartment of Synthesis and Technology of Drugs, Medical University of Bialystok, Jana Kilinskiego 1, 15-089 Bialystok, Poland.
Krzysztof BielawskiDepartment of Synthesis and Technology of Drugs, Medical University of Bialystok, Jana Kilinskiego 1, 15-089 Bialystok, Poland.

Funding

Uniwersytet Medyczny w Białymstoku SUB/2/DN/20/001/2217 and SUB/2/DN/20/002/2217
6 · The paper itself

Abstract

The high number of new cancer incidences and the associated mortality continue to be alarming, leading to the search for new therapies that would be more effective and less burdensome for patients. As there is evidence that Se compounds can have chemopreventive activity, studies have begun to establish whether these compounds can also affect already existing cancers. This review aims to discuss the different classes of Se-containing compounds, both organic and inorganic, natural and synthetic, and the mechanisms and molecular targets of their anticancer activity. The chemical classes discussed in this paper include inorganic (selenite, selenate) and organic compounds, such as diselenides, selenides, selenoesters, methylseleninic acid, 1,2-benzisoselenazole-3[2H]-one and selenophene-based derivatives, as well as selenoamino acids and Selol.

Indexed as

AnimalsAntineoplastic AgentsChemopreventionClinical Trials as TopicHumansNeoplasmsSelenium CompoundsAntineoplastic AgentsSelenium Compoundsanticancer agentscancerchemopreventioncombinatorial therapydrug resistancemolecular targetselenium compounds

Identifiers

PMID33498364
PMCPMC7864035

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.