Evidence map›Paper›PMID 33498351›Full record

ArticleInternational journal of molecular sciences2021

The Lactococcal

Aleksandra Tymoszewska, Tamara Aleksandrzak-Piekarczyk

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Polar-Region Soils as Novel Reservoir of Lactic Acid Bacteria from the GenusInternational journal of molecular sciences · 2024
    Article
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Aleksandra TymoszewskaInstitute of Biochemistry and Biophysics, Polish Academy of Sciences (IBB PAS), Pawińskiego 5a, 02-106 Warsaw, Poland.ORCID 0000-0002-7848-0679
Tamara Aleksandrzak-PiekarczykInstitute of Biochemistry and Biophysics, Polish Academy of Sciences (IBB PAS), Pawińskiego 5a, 02-106 Warsaw, Poland.ORCID 0000-0002-4725-760X
Institute of Biochemistry and Biophysics, Polish Academy of Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The emergence of antibiotic-resistant bacteria led to an urgent need for next-generation antimicrobial agents with novel mechanisms of action. The use of positively charged antimicrobial peptides that target cytoplasmic membrane is an especially promising strategy since essential functions and the conserved structure of the membrane hinder the development of bacterial resistance. Aureocin A53- and enterocin L50-like bacteriocins are highly cationic, membrane-targeting antimicrobial peptides that have potential as next-generation antibiotics. However, the mechanisms of resistance to these bacteriocins and cross-resistance against antibiotics must be examined before application to ensure their safe use. Here, in the model bacterium

Indexed as

Drug Resistance, BacterialAnti-Bacterial AgentsBacterial ProteinsBacteriocinsDiacylglycerol KinaseLactococcus lactisLipid MetabolismPhosphotransferases (Alcohol Group Acceptor)Polymorphism, Single NucleotideAnti-Bacterial AgentsBacterial ProteinsBacteriocinsDiacylglycerol KinasePhosphotransferases (Alcohol Group Acceptor)xylulokinaseaureocin A53- and enterocin L50-like bacteriocinsbacteriocins and antibiotic resistancecell envelope-acting antibioticslactococcin 972Lactococcus lactislipid metabolismnisin

Identifiers

PMID33498351
PMCPMC7864038
OpenAlexW3122439064

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.