Evidence map›Paper›PMID 33498295›Full record

ReviewMolecules (Basel, Switzerland)2021

Fate of Biodegradable Engineered Nanoparticles Used in Veterinary Medicine as Delivery Systems from a One Health Perspective.

Constantin Cerbu, Melanie Kah, Jason C White, Carlos E Astete, Cristina M Sabliov

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 33 citations in OpenAlex.

  1. Avian PathogenicVeterinary sciences · 2025
    Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Detection of Methicillin-ResistantVeterinary medicine international · 2022
    Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Constantin CerbuDepartment of Infectious Diseases, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, 400372 Cluj-Napoca, Romania.ORCID 0000-0002-4603-0956
Melanie KahSchool of Environment, The University of Auckland, Auckland 1010, New Zealand.ORCID 0000-0002-8705-9229
Jason C WhiteConnecticut Agricultural Experiment Station, New Haven, CT 06511, USA.
Carlos E AsteteBiological and Agricultural Engineering Department, Louisiana State University and LSU Agricultural Center, Baton Rouge, LA 70803, USA.ORCID 0000-0001-8130-9277
Cristina M SabliovBiological and Agricultural Engineering Department, Louisiana State University and LSU Agricultural Center, Baton Rouge, LA 70803, USA.
Louisiana State University Agricultural Center · USConnecticut Agricultural Experiment Station · USUniversity of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca · ROUniversity of Auckland · NZ

Funding

CNCS-UEFISCDI Romania PN-III-P1-1.1-MC-2019-0138European Social Found, Human Capital operational Programme 2014-2020 POCU/380/6/13/125171USDA National Institute of Food and Agriculture AFRI # 2018-07406USDA-NIFA Hatch #1008750
6 · The paper itself

Abstract

The field of veterinary medicine needs new solutions to address the current challenges of antibiotic resistance and the need for increased animal production. In response, a multitude of delivery systems have been developed in the last 20 years in the form of engineered nanoparticles (ENPs), a subclass of which are polymeric, biodegradable ENPs, that are biocompatible and biodegradable (pbENPs). These platforms have been developed to deliver cargo, such as antibiotics, vaccines, and hormones, and in general, have been shown to be beneficial in many regards, particularly when comparing the efficacy of the delivered drugs to that of the conventional drug applications. However, the fate of pbENPs developed for veterinary applications is poorly understood. pbENPs undergo biotransformation as they are transferred from one ecosystem to another, and these transformations greatly affect their impact on health and the environment. This review addresses nanoparticle fate and impact on animals, the environment, and humans from a One Health perspective.

Indexed as

Drug Delivery SystemsAnimalsBiodegradable PlasticsEcosystemNanoparticlesOne HealthVeterinary MedicineWater Pollutants, ChemicalBiodegradable PlasticsWater Pollutants, Chemicalantibioticshormonesnanoparticlesone healthvaccinesveterinary medicine

Identifiers

PMID33498295
PMCPMC7863917
OpenAlexW3124846420

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.