Evidence map›Paper›PMID 33498214›Full record

ArticleVaccines2021

Human Transcriptomic Response to the VSV-Vectored Ebola Vaccine.

Francesco Santoro, Alessia Donato, Simone Lucchesi, Sara Sorgi, Alice Gerlini, Marielle C Haks, Tom H M Ottenhoff, Patricia Gonzalez-Dias, Vsv-Ebovac Consortium, Vsv-Eboplus Consortium and 5 more

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Microbiology spectrum · 2026
    Article
  3. Article
  4. Human genetics of responses to vaccines.Clinical and experimental immunology · 2025
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Immune Memory After Respiratory Infection WithFrontiers in cellular and infection microbiology · 2022
    Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 4 countries.

Francesco SantoroLaboratory of Molecular Microbiology and Biotechnology (LAMMB), Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.ORCID 0000-0003-3052-3518
Alessia DonatoLaboratory of Molecular Microbiology and Biotechnology (LAMMB), Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.
Simone LucchesiLaboratory of Molecular Microbiology and Biotechnology (LAMMB), Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.ORCID 0000-0003-3545-7433
Sara SorgiLaboratory of Molecular Microbiology and Biotechnology (LAMMB), Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.ORCID 0000-0001-8305-4095
Alice GerliniMicrobiotec srl, 53100 Siena, Italy.
Marielle C HaksDepartment of Infectious Diseases, Leiden University Medical Center, 2333 Leiden, The Netherlands.ORCID 0000-0002-7538-1800
Tom H M OttenhoffDepartment of Infectious Diseases, Leiden University Medical Center, 2333 Leiden, The Netherlands.ORCID 0000-0003-3706-3403
Patricia Gonzalez-DiasDepartment of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, São Paulo 05508-020, Brazil.ORCID 0000-0002-6434-3841
Vsv-Ebovac Consortium
Vsv-Eboplus Consortium
Helder I NakayaDepartment of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, São Paulo 05508-020, Brazil.ORCID 0000-0001-5297-9108
Angela HuttnerDepartment of Pathology and Immunology, Faculty of Medicine, University of Geneva, 1211 Geneva, Switzerland.
Claire-Anne SiegristDepartment of Pathology and Immunology, Faculty of Medicine, University of Geneva, 1211 Geneva, Switzerland.ORCID 0000-0001-7984-8669
Donata MedagliniLaboratory of Molecular Microbiology and Biotechnology (LAMMB), Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.
Gianni PozziLaboratory of Molecular Microbiology and Biotechnology (LAMMB), Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.
University of Siena · ITLeiden University Medical Center · NLUniversidade de São Paulo · BRUniversity of Geneva · CH

Funding

Innovative Medicines Initiative 115842Innovative Medicines Initiative 116068
6 · The paper itself

Abstract

Ebolavirus Disease (EVD) is a severe haemorrhagic fever that occurs in epidemic outbreaks, with a high fatality rate and no specific therapies available. rVSVΔG-ZEBOV-GP (Ervebo

Indexed as

Ebolavirus Diseaselive viral vectorrecombinant VSVtranscriptomicsvaccineVSV-ZEBOV

Identifiers

PMID33498214
PMCPMC7908976
OpenAlexW3121267243

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.