Evidence map›Paper›PMID 33498209›Full record

ArticleInternational journal of molecular sciences2021

Reticular Basement Membrane Thickness Is Associated with Growth- and Fibrosis-Promoting Airway Transcriptome Profile-Study in Asthma Patients.

Stanislawa Bazan-Socha, Sylwia Buregwa-Czuma, Bogdan Jakiela, Lech Zareba, Izabela Zawlik, Aleksander Myszka, Jerzy Soja, Krzysztof Okon, Jacek Zarychta, Paweł Kozlik and 5 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Stanislawa Bazan-SochaDepartment of Internal Medicine, Jagiellonian University Medical College, 31-066 Krakow, Poland.ORCID 0000-0001-9634-0963
Sylwia Buregwa-CzumaCollege of Natural Sciences, Institute of Computer Science, University of Rzeszów, Pigonia 1, 35-310 Rzeszów, Poland.
Bogdan JakielaDepartment of Internal Medicine, Jagiellonian University Medical College, 31-066 Krakow, Poland.
Lech ZarebaCollege of Natural Sciences, Institute of Computer Science, University of Rzeszów, Pigonia 1, 35-310 Rzeszów, Poland.
Izabela ZawlikCentre for Innovative Research in Medical and Natural Sciences, Institute of Medical Sciences, Medical College, University of Rzeszów, Kopisto 2a, 35-959 Rzeszów, Poland.
Aleksander MyszkaCentre for Innovative Research in Medical and Natural Sciences, Institute of Medical Sciences, Medical College, University of Rzeszów, Kopisto 2a, 35-959 Rzeszów, Poland.ORCID 0000-0002-2931-7920
Jerzy SojaDepartment of Internal Medicine, Jagiellonian University Medical College, 31-066 Krakow, Poland.
Krzysztof OkonDepartment of Pathology, Jagiellonian University Medical College, Grzegorzecka 16, 31-531 Krakow, Poland.ORCID 0000-0002-1921-5007
Jacek ZarychtaDepartment of Internal Medicine, Jagiellonian University Medical College, 31-066 Krakow, Poland.
Paweł KozlikDepartment of Internal Medicine, Jagiellonian University Medical College, 31-066 Krakow, Poland.
Sylwia DziedzinaDepartment of Internal Medicine, Jagiellonian University Medical College, 31-066 Krakow, Poland.
Agnieszka PadjasDepartment of Internal Medicine, Jagiellonian University Medical College, 31-066 Krakow, Poland.
Krzysztof WojcikDepartment of Internal Medicine, Jagiellonian University Medical College, 31-066 Krakow, Poland.ORCID 0000-0001-9786-2499
Michal KepskiCollege of Natural Sciences, Institute of Computer Science, University of Rzeszów, Pigonia 1, 35-310 Rzeszów, Poland.
Jan G BazanCollege of Natural Sciences, Institute of Computer Science, University of Rzeszów, Pigonia 1, 35-310 Rzeszów, Poland.
Jagiellonian University · PLInstitute of Computer Science · PLUniversity of Rzeszów · PL

Funding

Narodowe Centrum Nauki DEC-2013/09/B/NZ5/00758 (to SB-S)
6 · The paper itself

Abstract

Airway remodeling in asthma is characterized by reticular basement membrane (RBM) thickening, likely related to epithelial structural and functional changes. Gene expression profiling of the airway epithelium might identify genes involved in bronchial structural alterations. We analyzed bronchial wall geometry (computed tomography (CT)), RBM thickness (histology), and the bronchial epithelium transcriptome profile (gene expression array) in moderate to severe persistent (

Indexed as

TranscriptomeAdultApoptosisAsthmaBasement MembraneBronchiFemaleFibrosisHumansImmunity, InnateMaleMiddle AgedOxidative Stressairway remodelingasthmabronchial epitheliumgene expression

Identifiers

PMID33498209
PMCPMC7863966
OpenAlexW3121622440

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.