Evidence map›Paper›PMID 33498201›Full record

ArticleBiomedicines2021

Cell Proliferation Is Strongly Associated with the Treatment Conditions of an ER Stress Inducer New Anti-Melanoma Drug in Melanoma Cell Lines.

István Szász, Viktória Koroknai, Vikas Patel, Tibor Hajdú, Tímea Kiss, Róza Ádány, Margit Balázs

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

István SzászMTA-DE Public Health Research Group, University of Debrecen, 4032 Debrecen, Hungary.
Viktória KoroknaiMTA-DE Public Health Research Group, University of Debrecen, 4032 Debrecen, Hungary.
Vikas PatelDoctoral School of Health Sciences, University of Debrecen, 4032 Debrecen, Hungary.
Tibor HajdúDepartment of Anatomy, Histology and Embryology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Tímea KissDepartment of Public Health and Epidemiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Róza ÁdányMTA-DE Public Health Research Group, University of Debrecen, 4032 Debrecen, Hungary.ORCID 0000-0002-9679-6669
Margit BalázsMTA-DE Public Health Research Group, University of Debrecen, 4032 Debrecen, Hungary.ORCID 0000-0002-4246-2321
University of Debrecen · HU

Funding

European Regional Development Fund GINOP-2.3.2-15-2016-00005Hungarian Academy of Sciences, Hungary MTA11010 and TK2016-78National Research Develkopment and Innovation Found, Hungary K-112327 and K-13575
6 · The paper itself

Abstract

HA15 is a new anti-melanoma drug that triggers endoplasmic reticulum (ER) stress and causes deleterious effects on melanoma cell viability due to autophagy and apoptosis, regardless of driver mutations or drug resistance. In this study, we investigated the effect of HA15 on the viability/proliferation of

Indexed as

apoptosisautophagyER stressHA15 anti-melanoma drugresistant cell linesRNA-Seq

Identifiers

PMID33498201
PMCPMC7908983
OpenAlexW3122216745

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.