ReviewChest2021
Treatment-Emergent Central Apnea: Physiologic Mechanisms Informing Clinical Practice.
Review in Chest, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 41 citations in OpenAlex.
- Prevalence and management of residual respiratory events in OSA patients treated with CPAP: a prospective observational clinical experience.Sleep & breathing = Schlaf & Atmung · 2026Observational
- ERS Congress 2025: highlights from the Sleep Disordered Breathing Assembly.ERJ open research · 2026Article
- Treatment-emergent central sleep apnea after initiation of hypoglossal nerve stimulator.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025Article
- Effect of switching from continuous positive airway pressure to bilevel positive airway pressure on symptoms of continuous positive airway pressure-related aerophagia: an observational study part two of a two-part series.Sleep & breathing = Schlaf & Atmung · 2025Observational
- Loop gain and central chemosensitivity assessment as a valuable tool in guiding treatment decisions for central sleep apnea in children.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025Article
- Treatment-emergent central sleep apnea resolves with lower inspiratory pressure.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025Article
- Insights, recommendations, and research priorities for central sleep apnea: report from an expert panel.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025Article
- Waves Under the Surface? Finding "Centralness" with Self-Similarity.Annals of the American Thoracic Society · 2025Article
- Impact of Hypopnoea Classifications on the Assessment of Sleep Disordered Breathing in Heart Failure.Cardiac failure review · 2025Review
- Case Report: Hypertensive encephalopathy presents with complex types of sleep breathing events.Frontiers in cardiovascular medicine · 2025Article
- Positive airway pressure delivery: overcoming old hurdles, exploring new frontiers.Frontiers in sleep · 2024Article
- Review
- Central Sleep Apnea in Adults: Diagnosis and Treatment.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2023Article
- Treatment-emergent central sleep apnoea managed by CPAP with adjunctive acetazolamide: A case report.Respirology case reports · 2022Article
- Brazilian Thoracic Association Consensus on Sleep-disordered Breathing.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2022Article
- Practice recommendations for the role of physiotherapy in the management of sleep disorders: the 2022 Brazilian Sleep Association Guidelines.Sleep science (Sao Paulo, Brazil)Review
Corrections and comments
- Commented on by
- Commented on byResponse.2022
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The purpose of this review was to describe our management approach to patients with treatment-emergent central sleep apnea (TECSA). The emergence of central sleep apnea during positive airway pressure therapy occurs in approximately 8% of titration studies for OSA, and it has been associated with several demographic, clinical, and polysomnographic factors, as well as factors related to the titration study itself. TECSA shares similar pathophysiology with central sleep apnea. In fact, central and OSA pathophysiologic mechanisms are inextricably intertwined, with ventilatory instability and upper airway narrowing occurring in both entities. TECSA is a "dynamic" process, with spontaneous resolution with ongoing positive airway pressure therapy in most patients, persistence in some, or appearing de novo in a minority of patients. Management strategy for TECSA aims to eliminate abnormal respiratory events, stabilize sleep architecture, and improve the underlying contributing medical comorbidities. CPAP therapy remains a standard therapy for TECSA. Expectant management is appropriate given its transient nature in most cases, whereas select patients would benefit from an early switch to an alternative positive airway pressure modality. Other treatment options include supplemental oxygen and pharmacologic therapy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.