Evidence map›Paper›PMID 33497637›Full record

ArticleCurrent biology : CB2021

Cilia Biology: You're It! Tagging Proteins for Ciliary Removal.

Eduardo D Gigante, Tamara Caspary

Abstract readComment
PubMed Publisher
In one paragraph

Article in Current biology : CB, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Ciliary Membrane Lipid Homeostasis in Health and Disease.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Eduardo D GiganteNeuroscience Graduate Program, Emory University, Atlanta, GA 30322, USA; Department of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA. Electronic address: Eduardo.gigante@emory.edu.
Tamara CasparyDepartment of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA. Electronic address: tcaspar@emory.edu.
Emory University · US

Funding

Defining the relationship of ciliary Arl13b and SmoothenedF31NS106755 · NINDS · EMORY UNIVERSITY · PI GIGANTE, EDUARDO D. · 2019 to 2020
$91k
NINDS NIH HHS F31 NS106755
6 · The paper itself

Abstract

Recent work has resolved the established links between β-arrestin 2 and the BBSome in controlling ciliary GPCR localization by showing that β-arrestin 2 regulates the addition of K63-linked ubiquitin chains to tag proteins for removal from the cilia via the BBSome.

Indexed as

CiliaProteinsBiologyProteins

Identifiers

PMID33497637
OpenAlexW3123835383

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.