Evidence map›Paper›PMID 33496876›Full record

ArticleJournal of medical systems2021

A Novel Block Imaging Technique Using Nine Artificial Intelligence Models for COVID-19 Disease Classification, Characterization and Severity Measurement in Lung Computed Tomography Scans on an Italian Cohort.

Mohit Agarwal, Luca Saba, Suneet K Gupta, Alessandro Carriero, Zeno Falaschi, Alessio Paschè, Pietro Danna, Ayman El-Baz, Subbaram Naidu, Jasjit S Suri

Abstract read
In one paragraph

Article in Journal of medical systems, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Perspectives on Artificial Intelligence in Nursing in Asia.Asian/Pacific Island nursing journal · 2024
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  5. Review
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  13. Review
  14. Audio texture analysis of COVID-19 cough, breath, and speech sounds.Biomedical signal processing and control · 2022
    Article
  15. Review
  16. Article
  17. Review
  18. Review
  19. Review
  20. Predicting the Disease Severity of Virus Infection.Advances in experimental medicine and biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mohit AgarwalCSE Department, Bennett University, Greater Noida, India.
Luca SabaDepartment of Radiology, Azienda Ospedaliero Universitaria di Cagliari, Cagliari, Monserrato, Italy.
Suneet K GuptaCSE Department, Bennett University, Greater Noida, India.
Alessandro CarrieroDepartment of Radiology, A.O.U, "Maggiore d.c." Universiy of Eastern Piedmont, Novara, Italy.
Zeno FalaschiDepartment of Radiology, A.O.U, "Maggiore d.c." Universiy of Eastern Piedmont, Novara, Italy.
Alessio PaschèDepartment of Radiology, A.O.U, "Maggiore d.c." Universiy of Eastern Piedmont, Novara, Italy.
Pietro DannaDepartment of Radiology, A.O.U, "Maggiore d.c." Universiy of Eastern Piedmont, Novara, Italy.
Ayman El-BazBiomedical Engineering Department, Louisville, KY, USA.
Subbaram NaiduElectrical Engineering Department, University of Minnesota, Duluth, MN, USA.
Jasjit S SuriStroke Diagnosis and Monitoring Division, AtheroPoint™, Roseville, CA, 95661, USA. jasjit.suri@atheropoint.com.ORCID http://orcid.org/0000-0002-4600-8513

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Computer Tomography (CT) is currently being adapted for visualization of COVID-19 lung damage. Manual classification and characterization of COVID-19 may be biased depending on the expert's opinion. Artificial Intelligence has recently penetrated COVID-19, especially deep learning paradigms. There are nine kinds of classification systems in this study, namely one deep learning-based CNN, five kinds of transfer learning (TL) systems namely VGG16, DenseNet121, DenseNet169, DenseNet201 and MobileNet, three kinds of machine-learning (ML) systems, namely artificial neural network (ANN), decision tree (DT), and random forest (RF) that have been designed for classification of COVID-19 segmented CT lung against Controls. Three kinds of characterization systems were developed namely (a) Block imaging for COVID-19 severity index (CSI); (b) Bispectrum analysis; and (c) Block Entropy. A cohort of Italian patients with 30 controls (990 slices) and 30 COVID-19 patients (705 slices) was used to test the performance of three types of classifiers. Using K10 protocol (90% training and 10% testing), the best accuracy and AUC was for DCNN and RF pairs were 99.41 ± 5.12%, 0.991 (p < 0.0001), and 99.41 ± 0.62%, 0.988 (p < 0.0001), respectively, followed by other ML and TL classifiers. We show that diagnostics odds ratio (DOR) was higher for DL compared to ML, and both, Bispecturm and Block Entropy shows higher values for COVID-19 patients. CSI shows an association with Ground Glass Opacities (0.9146, p < 0.0001). Our hypothesis holds true that deep learning shows superior performance compared to machine learning models. Block imaging is a powerful novel approach for pinpointing COVID-19 severity and is clinically validated.

Indexed as

AdultAgedAged, 80 and overArtificial IntelligenceCOVID-19Deep LearningFemaleHumansItalyLungMaleMiddle AgedReproducibility of ResultsSARS-CoV-2Severity of Illness IndexTomography, X-Ray ComputedAccuracyBispectrumBlock imagingComputer tomographyCOVID-19COVID severity indexEntropyLungMachine learningPandemicTissue characterization

Identifiers

PMID33496876
PMCPMC7835451

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.