Evidence map›Paper›PMID 33496382›Full record

ReviewGenesis (New York, N.Y. : 2000)2021

Aquatic models of human ciliary diseases.

Mark E Corkins, Vanja Krneta-Stankic, Malgorzata Kloc, Rachel K Miller

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Genesis (New York, N.Y. : 2000), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mark E CorkinsDepartment of Pediatrics, Pediatric Research Center, UTHealth McGovern Medical School, Houston, Texas, USA.ORCID 0000-0001-8261-6025
Vanja Krneta-StankicDepartment of Pediatrics, Pediatric Research Center, UTHealth McGovern Medical School, Houston, Texas, USA.ORCID 0000-0003-4163-1346
Malgorzata KlocHouston Methodist, Research Institute, Houston, Texas, USA.ORCID 0000-0002-5192-8584
Rachel K MillerDepartment of Pediatrics, Pediatric Research Center, UTHealth McGovern Medical School, Houston, Texas, USA.ORCID 0000-0001-6381-7198

Funding

Novel Role of Nephron Epithelialization in Nuclear SignalingR01DK115655 · NIDDK · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Rachel Katherine Miller · 2019 to 2026
$2.3M
Role of p53 in Kidney Development: Modeling Renal Anomalies of Li-Fraumeni PatientsR03DK118771 · NIDDK · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MILLER, RACHEL KATHERINE · 2018 to 2019
$231k
NIDDK NIH HHS R01 DK115655NIDDK NIH HHS R03 DK118771
6 · The paper itself

Abstract

Cilia are microtubule-based structures that either transmit information into the cell or move fluid outside of the cell. There are many human diseases that arise from malfunctioning cilia. Although mammalian models provide vital insights into the underlying pathology of these diseases, aquatic organisms such as Xenopus and zebrafish provide valuable tools to help screen and dissect out the underlying causes of these diseases. In this review we focus on recent studies that identify or describe different types of human ciliopathies and outline how aquatic organisms have aided our understanding of these diseases.

Indexed as

Disease Models, AnimalAnimalsCiliopathiesPhenotypeXenopus laevisZebrafishciliaciliopathycystic kidneykidneynasalnodeXenopuszebrafish

Identifiers

PMID33496382
PMCPMC8593908

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.