Evidence map›Paper›PMID 33496193›Full record

ArticleExpert review of anti-infective therapy2021

Drug discovery for primary amebic meningoencephalitis: from screen to identification of leads.

Anjan Debnath

Open access · greenAbstract read
In one paragraph

Article in Expert review of anti-infective therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Article
  3. The potential of nanocomposites (patuletin-conjugated with gallic acid-coated zinc oxide) against free-living amoebae pathogens.International microbiology : the official journal of the Spanish Society for Microbiology · 2025
    Article
  4. Wrangling Real-World Data: Optimizing Clinical Research Through Factor Selection with LASSO Regression.International journal of environmental research and public health · 2025
    Article
  5. Article
  6. Emerging patents versus brain eating amoebae,Pharmaceutical patent analyst · 2024
    Review
  7. Review
  8. Nanocarrier Drug Conjugates Exhibit Potent Anti-Diseases (Basel, Switzerland) · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Antiamoebic Properties of Metabolites againstAntibiotics (Basel, Switzerland) · 2022
    Article
  14. Frontiers in microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Anjan DebnathCenter for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0001-9294-3927
University of California San Diego · US

Funding

HMG-CoA Reductase Inhibitors as New Drug Leads for Naegleria InfectionR21AI146460 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DEBNATH, ANJAN · 2020 to 2021
$433k
NIAID NIH HHS R21 AI146460
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAntiprotozoal AgentsCentral Nervous System Protozoal InfectionsDrug DevelopmentDrug DiscoveryHigh-Throughput Screening AssaysHumansNaegleria fowleriRare DiseasesAntiprotozoal Agentsdrugshigh-throughputleadsNaegleria fowleriprimary amebic meningoencephalitisscreen

Identifiers

PMID33496193
PMCPMC8410612
OpenAlexW3122595002

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.