Evidence map›Paper›PMID 33496191›Full record

ArticleJournal of the American Heart Association2021

Predictors for Rapid Progression of Coronary Calcification: An Optical Coherence Tomography Study.

Akihiro Nakajima, Makoto Araki, Osamu Kurihara, Yoshiyasu Minami, Tsunenari Soeda, Taishi Yonetsu, Takumi Higuma, Tsunekazu Kakuta, Iris McNulty, Hang Lee and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Review
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  4. Article
  5. Review
  6. Article
  7. Review
  8. Renal Dysfunction Increases Risk of Adverse Cardiovascular Events in 5-Year Follow-Up Study of Intermediate Coronary Artery Lesions.Medical science monitor : international medical journal of experimental and clinical research · 2024
    Article
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  15. Layered Plaque in Organic Lesions in Patients With Coronary Artery Spasm.Journal of the American Heart Association · 2022
    Article
  16. Article
  17. Clinical Value and Potential Molecular Mechanism of miR-373-3p in Coronary Atherosclerosis.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 3 countries.

Akihiro NakajimaCardiology Division Massachusetts General HospitalHarvard Medical School Boston MA.
Makoto ArakiCardiology Division Massachusetts General HospitalHarvard Medical School Boston MA.
Osamu KuriharaCardiology Division Massachusetts General HospitalHarvard Medical School Boston MA.
Yoshiyasu MinamiDepartment of Cardiovascular Medicine Kitasato University School of Medicine Sagamihara Kanagawa Japan.
Tsunenari SoedaDepartment of Cardiovascular Medicine Nara Medical University Kashihara Nara Japan.
Taishi YonetsuDepartment of Interventional Cardiology Tokyo Medical and Dental University Tokyo Japan.
Takumi HigumaDivision of Cardiology Department of Internal Medicine St. Marianna University School of Medicine Kanagawa Japan.
Tsunekazu KakutaDepartment of Cardiology Tsuchiura Kyodo General Hospital Tsuchiura Ibaraki Japan.
Iris McNultyCardiology Division Massachusetts General HospitalHarvard Medical School Boston MA.
Hang LeeBiostatistics Center Massachusetts General HospitalHarvard Medical School Boston MA.
Rajeev MalhotraCardiology Division Massachusetts General HospitalHarvard Medical School Boston MA.
Sunao NakamuraInterventional Cardiology Unit New Tokyo Hospital Chiba Japan.
Ik-Kyung JangCardiology Division Massachusetts General HospitalHarvard Medical School Boston MA.
Harvard University · USKitasato University · JPNara Medical University · JPNew Tokyo Hospital · JPSt. Marianna University School of Medicine · JPTokyo Medical and Dental University · JPTsuchiura Kyodo General Hospital · JP

Funding

The Role of Histone Deacetylase 9 in Vascular CalcificationR01HL142809 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI MALHOTRA, RAJEEV · 2018 to 2022
$4.0M
NHLBI NIH HHS R01 HL142809
6 · The paper itself

Abstract

Background The role of coronary calcification in cardiovascular events and plaque stabilization is still being debated, and factors involved in the progression of coronary calcification are not fully understood. This study aimed to identify the predictors for rapid progression of coronary calcification. Methods and Results Patients with serial optical coherence tomography imaging at baseline and at 6 months were selected. Changes in the calcification index and predictors for progression of calcification were studied. Calcification index was defined as the product of the mean calcification arc and calcification length. Rapid progression of calcification was defined as an increase in the calcification index above the median value. Among 187 patients who had serial optical coherence tomography imaging, 235 calcified plaques were identified in 105 patients (56.1%) at baseline. After 6 months, the calcification index increased in 95.3% of calcified plaques from 132.0 to 178.2 (

Indexed as

RegistriesCoronary AngiographyCoronary Artery DiseaseCoronary VesselsDisease ProgressionFemaleFollow-Up StudiesHumansMaleMiddle AgedPredictive Value of TestsPrognosisRetrospective StudiesTomography, Optical CoherenceVascular Calcificationcalcificationinflammationlipid‐rich plaquemacrophageoptical coherence tomography

Identifiers

PMID33496191
PMCPMC7955445
OpenAlexW3122946050

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.