Evidence map›Paper›PMID 33496187›Full record

ArticleJournal of the American Heart Association2021

Papillary Muscles Abnormalities in Athletes With Otherwise Unexplained T-Wave Inversion in the ECG Lateral Leads.

Manuel De Lazzari, Alessandro Zorzi, Natascia Bettella, Alberto Cipriani, Kalliopi Pilichou, Marco Cason, Teresina Vessella, Patrizio Sarto, Maria Rita Gualea, Francesca Chianura and 7 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 1 country.

Manuel De LazzariDepartment of Cardiac, Thoracic and Vascular Sciences and Public Health University of Padova Italy.
Alessandro ZorziDepartment of Cardiac, Thoracic and Vascular Sciences and Public Health University of Padova Italy.
Natascia BettellaDepartment of Cardiac, Thoracic and Vascular Sciences and Public Health University of Padova Italy.
Alberto CiprianiDepartment of Cardiac, Thoracic and Vascular Sciences and Public Health University of Padova Italy.
Kalliopi PilichouDepartment of Cardiac, Thoracic and Vascular Sciences and Public Health University of Padova Italy.
Marco CasonDepartment of Cardiac, Thoracic and Vascular Sciences and Public Health University of Padova Italy.
Teresina VessellaCenter for Sports Medicine ULSS2 Marca Trevigiana Treviso Italy.
Patrizio SartoCenter for Sports Medicine ULSS2 Marca Trevigiana Treviso Italy.
Maria Rita GualeaInterdipartimental Center for Biology and Sports Medicine University of Pavia Italy.
Francesca ChianuraSan Raffaele Resnati/IRCCS Ospedale San Raffaele Milano Italy.
Lucia TardiniUOC Cardiologia Ospedale Ramazzini Carpi (MO) Italy.
Giuseppe RicciSan Tommaso Sports Medicine Center Ascoli Piceno Italy.
Ilaria MazzantiAzienda Sanitaria Regionale Marche Ancona Italy.
Fabrizio RicciDepartment of Neuroscience, Imaging and Clinical Sciences University of Chieti-Pescara Chieti Scalo Italy.
Raffaella MottaDepartment of Medicine, Radiology Unit University of Padova Padova Italy.
Martina Perazzolo MarraDepartment of Cardiac, Thoracic and Vascular Sciences and Public Health University of Padova Italy.
Domenico CorradoDepartment of Cardiac, Thoracic and Vascular Sciences and Public Health University of Padova Italy.
University of Padua · ITAULSS 2 Marca Trevigiana · ITIRCCS Ospedale San Raffaele · ITIstituto Ramazzini · ITUniversity of Chieti-Pescara · ITUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Papillary muscles (PMs) abnormalities may be associated with ECG repolarization abnormalities. We aimed to evaluate the relation between lateral T-wave inversion (TWI) and PMs characteristics in a cohort of athletes with no clinically demonstrable cardiac disease. Methods and Results We included 53 athletes (median age, 20 years; 87% men) with lateral TWI and no evidence of heart disease on clinical and cardiac magnetic resonance evaluation. A group of healthy athletes with normal ECG served as controls. We evaluated the PMs dimensions, such as diameters, area, volume, mass, and ratio between PMs and left ventricular mass, and the prevalence of PMs apical displacement. Compared with controls, athletes with TWI showed PMs hypertrophy with significantly increased PMs diameters, area, volume, and mass. The ratio between PMs and left ventricular mass was 4.4% in athletes with TWI and 3.0% in controls (

Indexed as

AthletesCardiomyopathy, HypertrophicElectrocardiographyFemaleFollow-Up StudiesHumansItalyMagnetic Resonance Imaging, CineMalePapillary MusclesPrevalenceSportsYoung Adultcardiac magnetic resonanceelectrocardiographyimagingpreparticipation screeningsports cardiology

Identifiers

PMID33496187
PMCPMC7955426
OpenAlexW3124895091

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.