Evidence map›Paper›PMID 33496164›Full record

ArticleMinerva medica2022

Airway smooth muscle and airway hyperresponsiveness in asthma: mechanisms of airway smooth muscle dysfunction.

Eric B Gebski, Omkar Anaspure, Reynold A Panettieri, Cynthia J Koziol-White

Abstract read
In one paragraph

Article in Minerva medica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Long-acting βRespiratory research · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Eric B GebskiRutgers Institute for Translational Medicine and Science, Rutgers University, New Brunswick, NJ, USA.
Omkar AnaspureRutgers Institute for Translational Medicine and Science, Rutgers University, New Brunswick, NJ, USA.
Reynold A PanettieriRutgers Institute for Translational Medicine and Science, Rutgers University, New Brunswick, NJ, USA.
Cynthia J Koziol-WhiteRutgers Institute for Translational Medicine and Science, Rutgers University, New Brunswick, NJ, USA - cjk167@rbhs.rutgers.edu.

Funding

Translational Research Support CoreP30ES005022 · NIEHS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI BRIAN T BUCKLEY · 1988 to 2026
$47.4M
Project 4 - OGR1- and TSPO- dependent mechanisms mediated by benzodiazepines affecting ASM contractionP01HL114471 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI LIGGETT, STEPHEN B · 2013 to 2023
$23.9M
Identification of new mechanistic biomarkers of adverse responses to acetaminopheR01DK081406 · NIDDK · ARKANSAS CHILDREN'S HOSPITAL RES INST · PI JAMES, LAURA P · 2009 to 2013
$1.9M
Mechanisms of Rhinovirus-induced airway hyperresponsiveness: an airway smooth muscle perspectiveR56HL142890 · NHLBI · RUTGERS BIOMEDICAL/HEALTH SCIENCES-RBHS · PI KOZIOL-WHITE, CYNTHIA · 2020 to 2020
$404k
NHLBI NIH HHS P01 HL114471NHLBI NIH HHS R56 HL142890NIDDK NIH HHS R01 DK081406NIEHS NIH HHS P30 ES005022
6 · The paper itself

Abstract

Airway smooth muscle plays a pivotal role in modulating bronchomotor tone. Modulation of contractile and relaxation signaling is critical to alleviate the airway hyperresponsiveness (AHR) associated with asthma. Emerging studies examining the phenotype of ASM in the context of asthma provide rich avenues to develop more effective therapeutics to attenuate the AHR associated with the disease.

Indexed as

AsthmaMuscle, SmoothHumansMuscle ContractionSignal Transduction

Identifiers

PMID33496164
PMCPMC9254130

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.