Evidence map›Paper›PMID 33495941›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2021

Expect the unexpected: fungemia caused by uncommon Candida species in a Turkish University Hospital.

Sehnaz Alp, Dolunay Gulmez, Rıza Can Kardas, Gizem Karahan, Zahit Tas, Gamze Gursoy, Caglayan Merve Ayaz-Ceylan, Sevtap Arikan-Akdagli, Murat Akova

Abstract read
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In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Meyerozyma guilliermondii species complex: review of current epidemiology, antifungal resistance, and mechanisms.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Sehnaz AlpFaculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Hacettepe University, 06100, Sihhiye, Ankara, Turkey. alpsehnaz@gmail.com.ORCID http://orcid.org/0000-0001-9424-8346
Dolunay GulmezFaculty of Medicine, Department of Medical Microbiology, Hacettepe University, Ankara, Turkey.
Rıza Can KardasFaculty of Medicine, Department of Internal Medicine, Hacettepe University, Ankara, Turkey.
Gizem KarahanFaculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Hacettepe University, 06100, Sihhiye, Ankara, Turkey.
Zahit TasFaculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Hacettepe University, 06100, Sihhiye, Ankara, Turkey.
Gamze GursoyFaculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Hacettepe University, 06100, Sihhiye, Ankara, Turkey.
Caglayan Merve Ayaz-CeylanFaculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Hacettepe University, 06100, Sihhiye, Ankara, Turkey.
Sevtap Arikan-AkdagliFaculty of Medicine, Department of Medical Microbiology, Hacettepe University, Ankara, Turkey.
Murat AkovaFaculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Hacettepe University, 06100, Sihhiye, Ankara, Turkey.
Hacettepe University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fungemia caused by uncommon Candida species (UCS) (other than C.albicans, C.glabrata, C.parapsilosis, C.tropicalis, C.krusei) is a rare but emerging threat with their potential to exhibit reduced susceptibility or resistance to antifungal agents. We identified 25 patients with UCS fungemia (9 C.kefyr, 8 C.lusitaniae, 4 C.dubliniensis, 2 C.guilliermondii, 1 C.pelliculosa, 1 C.rugosa) through January 2011 and August 2018. Echinocandins were the most common administered agents, followed by fluconazole. Overall mortality was 44%. Echinocandins and voriconazole showed sufficient activity against all tested isolates. High fluconazole MICs among C.guilliermondii, C.pelliculosa, and C.rugosa were determined. MIC value of C.pelliculosa was above the epidemiological cut-off proposed for fluconazole.

Indexed as

AdultAgedCandidaCandidemiaCross InfectionFemaleHospitals, UniversityHumansMaleMiddle AgedRetrospective StudiesRisk FactorsTurkeyAntifungal susceptibilityAntifungal treatmentBreakthrough fungemiaEpidemiological cut-off valueFungemiaUncommon Candida species

Identifiers

PMID33495941
OpenAlexW3124558822

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.