Evidence map›Paper›PMID 33495896›Full record

ArticlePediatric nephrology (Berlin, Germany)2021

Acute necrotizing glomerulonephritis associated with COVID-19 infection: report of two pediatric cases.

Mitra Basiratnia, Dorna Derakhshan, Babak Shirazi Yeganeh, Ali Derakhshan

Abstract readCase Reports
In one paragraph

Article in Pediatric nephrology (Berlin, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  11. Renal manifestations of COVID 19 in children.Journal of family medicine and primary care · 2022
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  16. Acute kidney injury in a patient with COVID-19: Answers.Pediatric nephrology (Berlin, Germany) · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mitra BasiratniaShiraz Nephro-Urology Research Center, Shiraz University of Medical Science, Shiraz, Iran.
Dorna DerakhshanShiraz Nephro-Urology Research Center, Shiraz University of Medical Science, Shiraz, Iran. Dornaderakhshan@yahoo.com.ORCID 0000-0003-1266-5539
Babak Shirazi YeganehPathology Department, Shiraz University of Medical Sciences, Shiraz, Iran.
Ali DerakhshanShiraz Nephro-Urology Research Center, Shiraz University of Medical Science, Shiraz, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoronavirus disease 2019 (COVID-19) is thought to cause kidney injury via a variety of mechanisms. The most common reported kidney injury following COVID-19 infection is acute tubular injury (ATI); however, the procoagulant state induced by the virus may also damage the kidneys. CASE-DIAGNOSIS/TREATMENT: Herein, we report two cases of acute necrotizing glomerulonephritis (GN) with fibrinoid necrosis in the context of COVID-19 infection. The one with more chronic features in the kidney biopsy progressed to permanent kidney failure but the second one had an excellent response to glucocorticoid pulse therapy with subsequent normal kidney function at 2-month follow-up.

conclusionsBoth reported cases had an acute presentation of kidney injury with positive nasopharyngeal PCR test for COVID-19. Based on the data review by the researchers, this is the first report of acute necrotizing GN associated with COVID-19 infection.

Indexed as

Acute Kidney InjuryAdolescentBiopsyBlood CoagulationCOVID-19GlomerulonephritisGlucocorticoidsHumansKidney GlomerulusMaleNecrosisPlatelet CountPulse Therapy, DrugRenal DialysisSARS-CoV-2Treatment OutcomeGlucocorticoidsCOVID-19DialysisKidneysNecrotizing glomerulonephritisPediatrics

Identifiers

PMID33495896
PMCPMC7834948

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.