Evidence map›Paper›PMID 33495739›Full record

ReviewHeliyon2021

Kidney diseases and COVID-19 infection: causes and effect, supportive therapeutics and nutritional perspectives.

Hassan Askari, Nima Sanadgol, Asaad Azarnezhad, Amir Tajbakhsh, Hossein Rafiei, Ali Reza Safarpour, Seyed Mohammad Gheibihayat, Ehsan Raeis-Abdollahi, Amir Savardashtaki, Ali Ghanbariasad and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Heliyon, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 44 citations in OpenAlex.

  1. Review
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  12. Review
  13. Impact of Kidney Failure on the Severity of COVID-19.Journal of clinical medicine · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 3 countries.

Hassan AskariGastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Nima SanadgolDepartment of Biology, Faculty of Sciences, University of Zabol, Zabol, Iran.
Asaad AzarnezhadCellular and Molecular Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran.
Amir TajbakhshPharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Hossein RafieiTerry Fox Laboratory, BC Cancer Research Centre, Vancouver, BC, Canada.
Ali Reza SafarpourGastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Seyed Mohammad GheibihayatDepartment of Medical Biotechnology, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Ehsan Raeis-AbdollahiDepartment of Physiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Amir SavardashtakiPharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Ali GhanbariasadNoncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran.
Navid OmidifarBiotechnology Research Center, Department of Pathology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Shiraz University of Medical Sciences · IRFasa University of Medical Sciences · IRKurdistan University of Medical Sciences · IRShahid Sadoughi University of Medical Sciences and Health Services · IRTehran University of Medical Sciences · IRTerry Fox Research Institute · CAZabol University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, the novel coronavirus disease 2019 (COVID-19), has attracted the attention of scientists where it has a high mortality rate among older adults and individuals suffering from chronic diseases, such as chronic kidney diseases (CKD). It is important to elucidate molecular mechanisms by which COVID-19 affects the kidneys and accordingly develop proper nutritional and pharmacological strategies. Although numerous studies have recently recommended several approaches for the management of COVID-19 in CKD, its impact on patients with renal diseases remains the biggest challenge worldwide. In this paper, we review the most recent evidence regarding causality, potential nutritional supplements, therapeutic options, and management of COVID-19 infection in vulnerable individuals and patients with CKD. To date, there is no effective treatment for COVID-19-induced kidney dysfunction, and current treatments are yet limited to anti-inflammatory (e.g. ibuprofen) and anti-viral medications (e.g. Remdesivir, and Chloroquine/Hydroxychloroquine) that may increase the chance of treatment. In conclusion, the knowledge about kidney damage in COVID-19 is very limited, and this review improves our ability to introduce novel approaches for future clinical trials for this contiguous disease.

Indexed as

COVID-19Kidney diseasesMulti-organ failureNutritional supplements

Identifiers

PMID33495739
PMCPMC7817396
OpenAlexW3122355567

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.