Evidence map›Paper›PMID 33495661›Full record

ArticlePattern recognition2021

Synergistic learning of lung lobe segmentation and hierarchical multi-instance classification for automated severity assessment of COVID-19 in CT images.

Kelei He, Wei Zhao, Xingzhi Xie, Wen Ji, Mingxia Liu, Zhenyu Tang, Yinghuan Shi, Feng Shi, Yang Gao, Jun Liu and 2 more

Open access · greenAbstract read
In one paragraph

Article in Pattern recognition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
13.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 109 citations in OpenAlex.

  1. Pooled it
  2. Role of Artificial Intelligence in COVID-19 Detection.Sensors (Basel, Switzerland) · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 3 countries.

Kelei HeMedical School of Nanjing University, Nanjing, China.
Wei ZhaoDepartment of Radiology, the Second Xiangya Hospital, Central South University, Changsha,Hunan, China.
Xingzhi XieDepartment of Radiology, the Second Xiangya Hospital, Central South University, Changsha,Hunan, China.
Wen JiNational Institute of Healthcare Data Science at Nanjing University, China.
Mingxia LiuBiomedical Research Imaging Center and the Department of Radiology, University of North Carolina, Chapel Hill, NC, U.S.
Zhenyu TangBeijing Advanced Innovation Center for Big Data and Brain Computing, Beihang University, Beijing, China.
Yinghuan ShiNational Institute of Healthcare Data Science at Nanjing University, China.
Feng ShiDepartment of Research and Development, Shanghai United Imaging Intelligence Co., Ltd., Shanghai, China.
Yang GaoNational Institute of Healthcare Data Science at Nanjing University, China.
Jun LiuDepartment of Radiology, the Second Xiangya Hospital, Central South University, Changsha,Hunan, China.
Junfeng ZhangMedical School of Nanjing University, Nanjing, China.
Dinggang ShenDepartment of Research and Development, Shanghai United Imaging Intelligence Co., Ltd., Shanghai, China.
Central South University · CNNanjing University · CNNanjing Medical University · CNBeijing Advanced Sciences and Innovation Center · CNKorea University · KRUnited Imaging Healthcare (China) · CNUniversity of North Carolina at Chapel Hill · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding chest CT imaging of the coronavirus disease 2019 (COVID-19) will help detect infections early and assess the disease progression. Especially, automated severity assessment of COVID-19 in CT images plays an essential role in identifying cases that are in great need of intensive clinical care. However, it is often challenging to accurately assess the severity of this disease in CT images, due to variable infection regions in the lungs, similar imaging biomarkers, and large inter-case variations. To this end, we propose a synergistic learning framework for automated severity assessment of COVID-19 in 3D CT images, by jointly performing lung lobe segmentation and multi-instance classification. Considering that only a few infection regions in a CT image are related to the severity assessment, we first represent each input image by a bag that contains a set of 2D image patches (with each cropped from a specific slice). A multi-task multi-instance deep network (called M

Indexed as

COVID-19CTLung lobe segmentationMulti-instance learningSeverity assessment

Identifiers

PMID33495661
PMCPMC7816595
OpenAlexW3120191671

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.