Could thermodynamics and heat and mass transfer research produce a fundamental step advance toward and significant reduction of SARS-COV-2 spread?

We are living an extraordinary season of uncertainty and danger, which is caused by SARS-Cov-2 infection and consequent COVID-19 infection. This preliminary study comes from both a mix of entrepreneurial experience and scientific research. It is aimed by the exigency to reach a new and more effective analysis of the risks on the filed and to reduce them inside a necessary cooperation process which may regard both research and some of the economic activities which are damaged by passive protection measures such as indiscriminate lockdowns. This global emergency requires specific efforts by any discipline that regards specific problems which need to be solved urgently. The characteristic airborne diffusion patterns of COVID-19 shows that the airborne presence of viruses depends on multiple factors which include the dimension of microdroplets emitted by a contagious person, the atmospheric temperature and humidity, the presence of atmospheric particulate and pollution, which may act as a transport vehicle for the virus. The pandemic diffusion shows a particular correlation with the air quality and levels of atmospheric pollution. Specific problems need to solved to understand better the virus, its reliability, diffusion, replication, how it attacks the persons and the conditions, which drives to both positive and deadly evolution of the illness. Most of these problems may benefit from the contribution from both heat and mass transfer and the unsteady thermodynamics of living systems which evolves according to constructal law. After the bibliographic research on the virus, emissive and spread modes, and consequent today adopted protection, a detailed analysis of the contributions which may be assessed by research in thermodynamics, heat and mass transfer, technical and chemical physics. Some possible areas of research have been identified and discussed to start an effective mobilization which may support the effort of the research toward a significant reduction of the impacts of the pandemic infection and the economic risks of new generalized lockdowns.