ArticleNature chemical biology2021
Chemical detection triggers honey bee defense against a destructive parasitic threat.
Article in Nature chemical biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 35 citations in OpenAlex.
- Evidence for virus-associated recapping behaviour in honey bees (Apis mellifera) with differential detection sensitivity between varroa-resistant and non-resistant colonies.Scientific reports · 2026Article
- Identification of two odorant receptors tuned to alarm pheromone compounds in the honey bee Apis mellifera.Communications biology · 2025Article
- Varroa Volatiles Offer Chemical Cues to Honey Bees for Initial Parasitic Recognition.Biomolecules · 2025Article
- Honey bees bred for Varroa sensitive hygiene trait demonstrate resistance to chalkbrood disease.PloS one · 2025Article
- Virucidal and cytotoxic properties of a natural honeybee hives-derived formulation suspended with marine plasma.Frontiers in cellular and infection microbiology · 2025Article
- Mechanisms of Pathogen and Pesticide Resistance in Honey Bees.Physiology (Bethesda, Md.) · 2024Review
- Mite non-reproduction is not a consequence of the brood removal behavior of varroa sensitive hygiene honey bee colonies (Ecology and evolution · 2024Article
- Honey bees (Apis mellifera) preselected for Varroa sensitive hygiene discriminate between live and dead Varroa destructor and inanimate objects.Scientific reports · 2023Article
- Detailed chemical analysis of honey bee (Apis mellifera) worker brood volatile profile from egg to emergence.PloS one · 2023Article
- Breeding honey bees (Frontiers in insect science · 2023Article
- Article
- Recapping and mite removal behaviour in Cuba: home to the world's largest population of Varroa-resistant European honeybees.Scientific reports · 2022Article
- Honey Bee Genetic Stock Determines Deformed Wing Virus Symptom Severity but not Viral Load or Dissemination Following Pupal Exposure.Frontiers in genetics · 2022Article
- Article
- Hygiene-Eliciting Brood Semiochemicals as a Tool for Assaying Honey Bee (Hymenoptera: Apidae) Colony Resistance to Varroa (Mesostigmata: Varroidae).Journal of insect science (Online) · 2021Article
- Suitability of drone olfactory sensitivity as a selection trait for Varroa-resistance in honeybees.Scientific reports · 2021Article
- Parallel evolution ofProceedings. Biological sciences · 2021Article
Corrections and comments
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Authors and funding
12 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Invasive species events related to globalization are increasing, resulting in parasitic outbreaks. Understanding of host defense mechanisms is needed to predict and mitigate against the consequences of parasite invasion. Using the honey bee Apis mellifera and the mite Varroa destructor, as a host-parasite model, we provide a comprehensive study of a mechanism of parasite detection that triggers a behavioral defense associated with social immunity. Six Varroa-parasitization-specific (VPS) compounds are identified that (1) trigger Varroa-sensitive hygiene (VSH, bees' key defense against Varroa sp.), (2) enable the selective recognition of a parasitized brood and (3) induce responses that mimic intrinsic VSH activity in bee colonies. We also show that individuals engaged in VSH exhibit a unique ability to discriminate VPS compounds from healthy brood signals. These findings enhance our understanding of a critical mechanism of host defense against parasites, and have the potential to apply the integration of pest management in the beekeeping sector.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.