Evidence map›Paper›PMID 33495552›Full record

ArticleNature reviews. Clinical oncology2021

Intraoperative radiotherapy for breast cancer: powerful evidence to change practice.

Jayant S Vaidya, Max Bulsara, Michael Baum, Michael Alvarado, Marcelle Bernstein, Samuele Massarut, Christobel Saunders, Elena Sperk, Frederik Wenz, Jeffrey S Tobias and 1 more

2 registry-linked trialsAbstract readLetterComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature reviews. Clinical oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04789889 naterminatednot on this map

Comparison of Satisfaction With Conserved Breast, Postoperative Complications and Tumor Control Between IORT and Postoperative Radiotherapy in Breast Conserving Surgery

TypeinterventionalSponsorXiangyun ZongRan2021 to 2025Enrolled80ConditionsQuality of LifeArmsintraoperative radiotherapy, postoperative radiotherapy
NCT06093854 nanot yet recruitingnot on this mapstarted 2024, after this paper: background citation

The Efficacy and Safety of Intraoperative Radiotherapy Vesus Stereotactic Body Radiotherapy in Managing Spinal Metastases: A Prospective, Single-center, Open-label, Non-inferior, Randomized Controlled Trial

TypeinterventionalSponsorShanghai Changzheng HospitalRan2024 to 2027Enrolled132ConditionsSpinal MetastasesArmsIntraoperative radiotherapy (IORT), Stereotactic body radiotherapy (SBRT)
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. The evolution of targeted intra operative radiotherapy in early breast cancer.Journal of cancer research and clinical oncology · 2025
    Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Jayant S VaidyaDivision of Surgery and Interventional Science, University College London, London, UK. jayantvaidya@gmail.com.ORCID http://orcid.org/0000-0003-1760-1278
Max BulsaraDivision of Surgery and Interventional Science, University College London, London, UK.
Michael BaumDivision of Surgery and Interventional Science, University College London, London, UK.
Michael AlvaradoDepartment of Surgery, University of California, San Francisco, CA, USA.
Marcelle Bernstein, London, UK.
Samuele MassarutDepartment of Surgery, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy.
Christobel SaundersSchool of Surgery, University of Western Australia, Perth, WA, Australia.
Elena SperkUniversity Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany.
Frederik WenzUniversity Medical Center Freiburg, Freiburg, Germany.
Jeffrey S TobiasDepartment of Clinical Oncology, University College London Hospitals, London, UK.
TARGIT-A investigators

Funding

Department of Health 10/104/07Department of Health 14/49/13Department of Health HTA 07/60/49
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Breast NeoplasmsMastectomy, SegmentalHumansNeoplasm Recurrence, LocalRadiotherapy, Adjuvant

Identifiers

PMID33495552
PMCPMC7830040

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.