Evidence map›Paper›PMID 33495489›Full record

Trial reportScientific reports2021

Ventilatory response to hypercapnia is increased after 4 h of head down bed rest.

K R Murray, S Wasef, Heather Edgell

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

K R Murray *School of Kinesiology and Health Science, York University, 355 Bethune College, 4700 Keele St, Toronto, ON, M3J 1P3, Canada.
S Wasef *School of Kinesiology and Health Science, York University, 355 Bethune College, 4700 Keele St, Toronto, ON, M3J 1P3, Canada.
Heather EdgellSchool of Kinesiology and Health Science, York University, 355 Bethune College, 4700 Keele St, Toronto, ON, M3J 1P3, Canada. edgell@yorku.ca.ORCID 0000-0001-8865-1921
York University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Head-down bed rest (HDBR) has previously been shown to alter cerebrovascular and autonomic control. Previous work found that sustained HDBR (≥ 20 days) attenuates the hypercapnic ventilatory response (HCVR); however, little is known about shorter-term effects of HDBR nor the influence of HDBR on the hypoxic ventilatory response (HVR). We investigated the effect of 4-h HDBR on HCVR and HVR and hypothesized attenuated ventilatory responses due to greater carotid and brain blood flow. Cardiorespiratory responses of young men (n = 11) and women (n = 3) to 5% CO

Indexed as

Bed RestHead-Down TiltRespirationBlood PressureFemaleHeart RateHumansHypercapniaHypoxiaMaleMiddle Cerebral ArteryPressoreceptorsStroke VolumeTidal VolumeVascular ResistanceYoung Adult

Identifiers

PMID33495489
PMCPMC7835380
OpenAlexW3123824594

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.