Evidence map›Paper›PMID 33495382›Full record

ArticleOpen heart2021

Predicting clinical outcome by indexed mitral valve tenting in functional mitral valve regurgitation.

Maria von Stumm, Florian Dudde, Theresa Holst, Tatjana Sequeira-Gross, Jonas Pausch, Lisa Müller, Christoph R Sinning, Hermann Reichenspurner, E Girdauskas

Open access · goldAbstract read
In one paragraph

Article in Open heart, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Mitral Regurgitation in Female Patients: Sex Differences and Disparities.Journal of the Society for Cardiovascular Angiography & Interventions
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Maria von StummCardiovascular Surgery, University Hospital Hamburg Eppendorf University Heart Centre, Hamburg, Germany m.stumm@uke.de.ORCID 0000-0001-9578-0430
Florian DuddeCardiovascular Surgery, University Hospital Hamburg Eppendorf University Heart Centre, Hamburg, Germany.
Theresa HolstCardiovascular Surgery, University Hospital Hamburg Eppendorf University Heart Centre, Hamburg, Germany.
Tatjana Sequeira-GrossCardiovascular Surgery, University Hospital Hamburg Eppendorf University Heart Centre, Hamburg, Germany.
Jonas PauschCardiovascular Surgery, University Hospital Hamburg Eppendorf University Heart Centre, Hamburg, Germany.
Lisa MüllerCardiovascular Surgery, University Hospital Hamburg Eppendorf University Heart Centre, Hamburg, Germany.
Christoph R SinningGeneral and Interventional Cardiology, University Hospital Hamburg Eppendorf University Heart Centre, Hamburg, Germany.ORCID 0000-0002-7331-8840
Hermann ReichenspurnerCardiovascular Surgery, University Hospital Hamburg Eppendorf University Heart Centre, Hamburg, Germany.
E GirdauskasCardiovascular Surgery, University Hospital Hamburg Eppendorf University Heart Centre, Hamburg, Germany.
Universität Hamburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesMitral valve (MV) tenting parameters are indicators of left ventricular remodelling severity and may predict outcome in functional mitral regurgitation (FMR). We hypothesised that indexing of MV tenting area to body surface area (BSA), to mitral annulus diameter or gender-adjusted analysis of tenting parameters may improve their prognostic value.

methodsWe identified retrospectively 240 patients with consecutive FMR (mean age 68±10 years; men=135) from our institutional database who underwent isolated MV annuloplasty during a period of 7 years (2010-2016). Using preoperative two-dimensional transthoracic echocardiographic images, MV tenting parameters including tenting area, tenting height and annulus diameter were systematically assessed. Follow-up protocol consisted of chart review and structured clinical questionnaire. Primary study endpoint was the composite of death and adverse cardiac events (ie, MV reoperation, cardiac resynchronisation therapy implantation, ventricular assist device implantation or heart transplantation).

resultsBSA-indexed MV tenting area was identified as independent predictor of primary study endpoint (HR 1.9; 95% CI 1.1 to 3.5; p=0.02). After cut-off point analysis, BSA-indexed MV tenting area >1.35 cm

conclusionIn our FMR cohort, BSA-indexed MV tenting area showed the strongest association with negative outcomes following isolated MV annuloplasty. Patients with BSA-indexed MV tenting area >1.35cm

Indexed as

AgedEchocardiography, Three-DimensionalFemaleFollow-Up StudiesHumansMaleMitral ValveMitral Valve AnnuloplastyMitral Valve InsufficiencyPrognosisRetrospective StudiesVentricular Remodelingcardiomyopathydilatedechocardiographymitral valve insufficiency

Identifiers

PMID33495382
PMCPMC7839912
OpenAlexW3122625655

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.