Evidence map›Paper›PMID 33495362›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Dog domestication and the dual dispersal of people and dogs into the Americas.

Angela R Perri, Tatiana R Feuerborn, Laurent A F Frantz, Greger Larson, Ripan S Malhi, David J Meltzer, Kelsey E Witt

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed.

  1. Article
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  5. Article
  6. Wolves respond differently to human cues as they expand into urban landscapes.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. A 120-y time series of genomes reveals the consequences of closed breeding in German Shepherd Dogs.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. A legacy of genetic entanglement with wolves shapes modern dogs.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  12. Imputation of ancient canid genomes reveals inbreeding history over the past 10,000 years.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  13. Genotypic and phenotypic consequences of domestication in dogs.bioRxiv : the preprint server for biology · 2025
    Article
  14. Review
  15. Review
  16. Review
  17. Linking individual fitness to the evolution of cognition.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  18. A universally applicable definition for domestication.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  19. Article
  20. Article

18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Angela R PerriDepartment of Archaeology, Durham University, Durham DH1 3LE, United Kingdom; angela.r.perri@durham.ac.uk dmeltzer@smu.edu kelsey_witt_dillon@brown.edu.ORCID 0000-0002-4349-1060
Tatiana R FeuerbornGLOBE Institute, University of Copenhagen, 1350 Copenhagen, Denmark.ORCID 0000-0003-1610-3402
Laurent A F FrantzPalaeogenomics Group, Department of Veterinary Sciences, Ludwig Maximilian University, Munich D-80539, Germany.
Greger LarsonThe Palaeogenomics and Bio-Archaeology Research Network, Research Laboratory for Archaeology and History of Art, University of Oxford, Oxford OX1 3QY, United Kingdom.ORCID 0000-0002-4092-0392
Ripan S MalhiDepartment of Anthropology, University of Illinois at Urbana-Champaign, Urbana, IL 61801.ORCID 0000-0002-1484-0292
David J MeltzerDepartment of Anthropology, Southern Methodist University, Dallas, TX 75205; angela.r.perri@durham.ac.uk dmeltzer@smu.edu kelsey_witt_dillon@brown.edu.ORCID 0000-0001-8084-9802
Kelsey E WittDepartment of Ecology and Evolutionary Biology, Brown University, Providence, RI 02912; angela.r.perri@durham.ac.uk dmeltzer@smu.edu kelsey_witt_dillon@brown.edu.ORCID 0000-0002-3242-2123

Funding

Characterizing modes of natural selection via diverse ancient and modern samplesR35GM128946 · NIGMS · BROWN UNIVERSITY · PI Emilia Huerta-Sanchez · 2018 to 2026
$3.1M
NIGMS NIH HHS R35 GM128946Wellcome Trust
6 · The paper itself

Abstract

Advances in the isolation and sequencing of ancient DNA have begun to reveal the population histories of both people and dogs. Over the last 10,000 y, the genetic signatures of ancient dog remains have been linked with known human dispersals in regions such as the Arctic and the remote Pacific. It is suspected, however, that this relationship has a much deeper antiquity, and that the tandem movement of people and dogs may have begun soon after the domestication of the dog from a gray wolf ancestor in the late Pleistocene. Here, by comparing population genetic results of humans and dogs from Siberia, Beringia, and North America, we show that there is a close correlation in the movement and divergences of their respective lineages. This evidence places constraints on when and where dog domestication took place. Most significantly, it suggests that dogs were domesticated in Siberia by ∼23,000 y ago, possibly while both people and wolves were isolated during the harsh climate of the Last Glacial Maximum. Dogs then accompanied the first people into the Americas and traveled with them as humans rapidly dispersed into the continent beginning ∼15,000 y ago.

Indexed as

DomesticationHuman MigrationAmericasAnimal MigrationAnimalsDogsGeographyHaplotypesHumansPhylogenySiberiaTime Factorsarchaeologydogsdomesticationgeneticspeopling of the Americas

Identifiers

PMID33495362
PMCPMC8017920

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.