Evidence map›Paper›PMID 33495343›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Virus-like insertions with sequence signatures similar to those of endogenous nonretroviral RNA viruses in the human genome.

Shohei Kojima, Kohei Yoshikawa, Jumpei Ito, So Nakagawa, Nicholas F Parrish, Masayuki Horie, Shuichi Kawano, Keizo Tomonaga

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

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  9. Mapping the evolution of bornaviruses across geological timescales.Proceedings of the National Academy of Sciences of the United States of America · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Shohei KojimaLaboratory of RNA Viruses, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan.
Kohei YoshikawaDepartment of Computer and Network Engineering, Graduate School of Informatics and Engineering, The University of Electro-Communications, Tokyo 182-8585, Japan.
Jumpei ItoDivision of Systems Virology, Department of Infectious Disease Control, International Research Center for Infectious Diseases, Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan.ORCID 0000-0003-0440-8321
So NakagawaDepartment of Molecular Life Science, Tokai University School of Medicine, Isehara 259-1193, Japan.
Nicholas F ParrishGenome Immunobiology RIKEN Hakubi Research Team, RIKEN Cluster for Pioneering Research, Yokohama 230-0045, Japan.
Masayuki HorieLaboratory of RNA Viruses, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan.ORCID 0000-0003-4682-7698
Shuichi KawanoDepartment of Computer and Network Engineering, Graduate School of Informatics and Engineering, The University of Electro-Communications, Tokyo 182-8585, Japan; skawano@ai.lab.uec.ac.jp tomonaga@infront.kyoto-u.ac.jp.ORCID 0000-0002-0804-0141
Keizo TomonagaLaboratory of RNA Viruses, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan; skawano@ai.lab.uec.ac.jp tomonaga@infront.kyoto-u.ac.jp.ORCID 0000-0003-0405-7103
Kyoto University · JPUniversity of Electro-Communications · JPNational Institute of Infectious Diseases · JPTokai University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding the genetics and taxonomy of ancient viruses will give us great insights into not only the origin and evolution of viruses but also how viral infections played roles in our evolution. Endogenous viruses are remnants of ancient viral infections and are thought to retain the genetic characteristics of viruses from ancient times. In this study, we used machine learning of endogenous RNA virus sequence signatures to identify viruses in the human genome that have not been detected or are already extinct. Here, we show that the

Indexed as

Genome, HumanAnimalsBase SequenceHumansMachine LearningMammalsMutagenesis, InsertionalNucleoproteinsRetroviridaeNucleoproteinsendogenous RNA virushuman genomemachine learningpaleovirology

Identifiers

PMID33495343
PMCPMC7865133
OpenAlexW3123648429

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.