Evidence map›Paper›PMID 33494965›Full record

ArticleVaccine2021

Costs implications of pneumococcal vaccination of adults aged 30-60 with a recent diagnosis of diabetes.

David W Hutton, Jeffrey S McCullough, Lisa Prosser, Wen Ye, William H Herman, Ping Zhang, Tamara Pilishvili, Jamison Pike

Open access · greenAbstract read
In one paragraph

Article in Vaccine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

David W HuttonDepartment of Health Management and Policy, University of Michigan, United States. Electronic address: dwhutton@umich.edu.
Jeffrey S McCulloughDepartment of Health Management and Policy, University of Michigan, United States.
Lisa ProsserDepartment of Health Management and Policy, University of Michigan, United States; Department of Pediatrics and Communicable Diseases, University of Michigan, United States.
Wen YeDepartment of Biostatistics, University of Michigan, United States.
William H HermanDepartments of Internal Medicine and Epidemiology, University of Michigan, United States.
Ping ZhangCenters for Disease Control and Prevention, United States.
Tamara PilishviliCenters for Disease Control and Prevention, United States.
Jamison PikeCenters for Disease Control and Prevention, United States.
University of Michigan · USCenters for Disease Control and Prevention · US

Funding

Joint Initiative in Vaccine Economics 5U01IP000965 · IP · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HUTTON, DAVID W · 2015 to 2017
$899k
ACL HHS U01IP000965Intramural CDC HHS CC999999NCIRD CDC HHS U01 IP000965
6 · The paper itself

Abstract

objectiveThe 23-valent pneumococcal polysaccharide vaccine is routinely recommended for adults with diabetes, but little is known about adherence to this recommendation and how vaccination of these adults affects costs related to pneumococcal disease. RESEARCH DESIGN AND

methodsWe used data from a commercial insurance claims dataset to examine a cohort of non-elderly adults with a new diagnosis of diabetes and adults with no diagnosis of diabetes from 2005 to 2014. We examined rates of pneumococcal polysaccharide vaccination and the relationship between vaccination and pneumococcal disease costs, comparing results for persons with a diagnosis of diabetes and those with no diagnosis of diabetes.

resultsOverall rates of pneumococcal polysaccharide vaccination among adults 30-60 years old were <1%/year. Rates of pneumococcal polysaccharide vaccination were higher for adults with diabetes. Pneumococcal polysaccharide vaccination rates more than doubled from 2.9% per year in 2005 to 6.0% per year in 2014 for adults vaccinated during the same year as their diabetes diagnosis. Using a two-part differences-in-differences model on a propensity-score matched dataset, pneumococcal polysaccharide vaccination may reduce average annual per-person pneumococcal disease costs by $90.54 [95% CI: $183.59, -$2.49, (p = 0.056)] in persons with diabetes from two years before to two years after vaccination.

conclusionsNon-elderly adults with diabetes have low but rising rates of pneumococcal polysaccharide vaccination. Pneumococcal polysaccharide vaccination has a modest impact reducing overall costs of pneumococcal disease in this population.

Indexed as

Diabetes MellitusPneumococcal InfectionsPneumonia, PneumococcalAdultCohort StudiesHumansMiddle AgedPneumococcal VaccinesVaccinationPneumococcal Vaccines

Identifiers

PMID33494965
PMCPMC9018094
OpenAlexW3125575648

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.