Evidence map›Paper›PMID 33494760›Full record

ArticleJournal of orthopaedic surgery and research2021

Performance of age-adjusted D-dimer values for predicting DVT before the knee and hip arthroplasty.

Jian Xiang Wu, Jiang Hui Qing, Yao Yao, Dong Yang Chen, Qing Jiang

Abstract read
In one paragraph

Article in Journal of orthopaedic surgery and research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  4. [Analysis of correlation between Barthel index score and preoperative occurrence of deep vein thrombosis in patients undergoing total hip arthroplasty revision surgery].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025
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  12. [Research advances on venous thromboembolism in burn patients].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2023
    Review
  13. Utility of D-dimer in total joint arthroplasty.World journal of orthopedics · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jian Xiang WuDepartment of Sports Medicine and Adult Reconstructive Surgery, Drum Tower Hospital, School of Nanjing Medical University, 321 Zhongshan Road, Nanjing, 210008, Jiangsu, P.R. China.
Jiang Hui QingState Key Laboratory of Pharmaceutical Biotechnology, Department of Sports Medicine and Adult Reconstructive Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, 321 Zhongshan Road, Nanjing, 210008, Jiangsu, P.R. China.
Yao YaoState Key Laboratory of Pharmaceutical Biotechnology, Department of Sports Medicine and Adult Reconstructive Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, 321 Zhongshan Road, Nanjing, 210008, Jiangsu, P.R. China.
Dong Yang ChenState Key Laboratory of Pharmaceutical Biotechnology, Department of Sports Medicine and Adult Reconstructive Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, 321 Zhongshan Road, Nanjing, 210008, Jiangsu, P.R. China.
Qing JiangState Key Laboratory of Pharmaceutical Biotechnology, Department of Sports Medicine and Adult Reconstructive Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, 321 Zhongshan Road, Nanjing, 210008, Jiangsu, P.R. China. qingj@nju.edu.cn.ORCID http://orcid.org/0000-0002-2552-9686

Funding

Basic Research Program of Jiangsu Province 20170123Key Program of NSFC 81730067National Natural Science Foundation of China 81972124
6 · The paper itself

Abstract

purposeTo compare the specificity and sensitivity of preoperative D-dimer and age-adjusted D-dimer value for predicting the incidence of the DVT preoperatively in total joint arthroplasty (TJA) patients.

methodsWe enrolled 406 patients finally above 50 years old. Everyone had done ultrasonography bedside, and D-dimer concentrations were collected before surgery. The D-dimer and age-adjusted D-dimer cut-off was calculated by multiple logistic regression and receiver operating curve (ROC) analyses.

resultsA total of 39 patients had found asymptomatic deep vein thrombosis (DVT) by ultrasonography. The age (odds ratio [OR] 1.067; p = 0.003) and D-dimer (OR 1.331; p = 0.025) were related to the existence of DVT. For conventional D-dimer and age-adjusted D-dimer value, the area under the curves (AUCs) were 0.685 (0.499-0.696) and 0.795 (0.611-0.881), respectively.

conclusionCompared to traditional D-dimer, age-adjusted D-dimer showed better performance in screening DVT, which was useful clinically.

Indexed as

AgedArthroplasty, Replacement, HipArthroplasty, Replacement, KneeBiomarkersFemaleFibrin Fibrinogen Degradation ProductsHumansLogistic ModelsMaleMiddle AgedPostoperative ComplicationsPredictive Value of TestsPreoperative PeriodROC CurveSensitivity and SpecificityVenous ThrombosisBiomarkersFibrin Fibrinogen Degradation Productsfibrin fragment D

Identifiers

PMID33494760
PMCPMC7831181

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.