Evidence map›Paper›PMID 33494524›Full record

ReviewPlants (Basel, Switzerland)2021

Bryo-Activities: A Review on How Bryophytes Are Contributing to the Arsenal of Natural Bioactive Compounds against Fungi.

Mauro Commisso, Francesco Guarino, Laura Marchi, Antonella Muto, Amalia Piro, Francesca Degola

Open access · goldAbstract readReview
In one paragraph

Review in Plants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
22.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 84 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Plant-fungi interactions inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Article
  6. Article
  7. Plants (Basel, Switzerland) · 2025
    Article
  8. Review
  9. Review
  10. The evolution of plant responses underlying specialized metabolism in host-pathogen interactions.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Mauro CommissoDepartment of Biotechnology, University of Verona, Cà Vignal 1, Strada Le Grazie 15, 37134 Verona (VR), Italy.ORCID 0000-0001-6474-8577
Francesco GuarinoDepartment of Chemistry and Biology, University of Salerno, Via Giovanni Paolo II 132, 84084 Fisciano (SA), Italy.ORCID 0000-0001-8536-4257
Laura MarchiDepartment of Medicine and Surgery, Respiratory Disease and Lung Function Unit, University of Parma, Via Gramsci 14, 43125 Parma (PR), Italy.
Antonella MutoDepartment of Biology, Ecology and Earth Sciences, University of Calabria, Via Ponte P. Bucci 6b, Arcavacata di Rende, 87036 Cosenza (CS), Italy.
Amalia PiroLaboratory of Plant Biology and Plant Proteomics (Lab.Bio.Pro.Ve), Department of Chemistry and Chemical Technologies, University of Calabria, Ponte P. Bucci 12 C, Arcavacata di Rende, 87036 Cosenza (CS), Italy.ORCID 0000-0002-6296-621X
Francesca DegolaDepartment of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parco delle Scienze 11/A, 43124 Parma (PR), Italy.ORCID 0000-0002-3937-251X
University of Calabria · ITUniversity of Parma · ITUniversity of Salerno · ITUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Usually regarded as less evolved than their more recently diverged vascular sisters, which currently dominate vegetation landscape, bryophytes seem having nothing to envy to the defensive arsenal of other plants, since they had acquired a suite of chemical traits that allowed them to adapt and persist on land. In fact, these closest modern relatives of the ancestors to the earliest terrestrial plants proved to be marvelous chemists, as they traditionally were a popular remedy among tribal people all over the world, that exploit their pharmacological properties to cure the most different diseases. The phytochemistry of bryophytes exhibits a stunning assortment of biologically active compounds such as lipids, proteins, steroids, organic acids, alcohols, aliphatic and aromatic compounds, polyphenols, terpenoids, acetogenins and phenylquinones, thus it is not surprising that substances obtained from various species belonging to such ancestral plants are widely employed as antitumor, antipyretic, insecticidal and antimicrobial. This review explores in particular the antifungal potential of the three Bryophyta divisions-mosses (Musci), hornworts (Anthocerotae) and liverworts (Hepaticae)-to be used as a sources of interesting bioactive constituents for both pharmaceutical and agricultural areas, providing an updated overview of the latest relevant insights.

Indexed as

bryophyteshornwortsliverwortsmossesnatural antifungalsplant extractsplants bioactive compounds from early-diverged land

Identifiers

PMID33494524
PMCPMC7911284
OpenAlexW3123436460

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.