Evidence map›Paper›PMID 33494451›Full record

ArticleMolecules (Basel, Switzerland)2021

Heme Binding to HupZ with a C-Terminal Tag from Group A Streptococcus.

Ephrahime S Traore, Jiasong Li, Tapiwa Chiura, Jiafeng Geng, Ankita J Sachla, Francis Yoshimoto, Zehava Eichenbaum, Ian Davis, Piotr J Mak, Aimin Liu

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Frontiers in bioengineering and biotechnology · 2022
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ephrahime S TraoreDepartment of Chemistry, The University of Texas at San Antonio, San Antonio, TX 78249, USA.ORCID 0000-0001-6419-9248
Jiasong LiDepartment of Chemistry, The University of Texas at San Antonio, San Antonio, TX 78249, USA.ORCID 0000-0003-0341-2038
Tapiwa ChiuraDepartment of Chemistry, Saint Louis University, St. Louis, MO 63103, USA.ORCID 0000-0002-4114-820X
Jiafeng GengDepartment of Chemistry, Georgia State University, Atlanta, GA 30302, USA.ORCID 0000-0001-9488-0974
Ankita J SachlaDepartment of Biology, Georgia State University, Atlanta, GA 30302, USA.ORCID 0000-0002-3850-5421
Francis YoshimotoDepartment of Chemistry, The University of Texas at San Antonio, San Antonio, TX 78249, USA.ORCID 0000-0002-2308-2999
Zehava EichenbaumDepartment of Biology, Georgia State University, Atlanta, GA 30302, USA.
Ian DavisDepartment of Chemistry, The University of Texas at San Antonio, San Antonio, TX 78249, USA.
Piotr J MakDepartment of Chemistry, Saint Louis University, St. Louis, MO 63103, USA.
Aimin LiuDepartment of Chemistry, The University of Texas at San Antonio, San Antonio, TX 78249, USA.

Funding

X-ray Absorption Spectroscopy (XAS) pp.711-759P41GM103393 · NIGMS · STANFORD UNIVERSITY · PI HODGSON, KEITH O · 2012 to 2019
$30.6M
Heme-dependent chemistry in tyrosine oxidation: Diversity Supplement on 5R01GM108988-08 for supporting Samuel MontoyaR01GM108988 · NIGMS · UNIVERSITY OF TEXAS SAN ANTONIO · PI LIU, AIMIN · 2014 to 2025
$4.2M
Role of STEAP2 protein in hepatocarcinogenesisR01CA247379 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI SUN, LUZHE · 2020 to 2024
$2.2M
NCI NIH HHS R01 CA247379NIGMS NIH HHS P41 GM103393NIGMS NIH HHS R01 GM108988NIH HHS CA247379NIH HHS GM108988
6 · The paper itself

Abstract

HupZ is an expected heme degrading enzyme in the heme acquisition and utilization pathway in Group A Streptococcus. The isolated HupZ protein containing a C-terminal V5-His

Indexed as

Bacterial ProteinsHemeProtein BindingRecombinant Fusion ProteinsStreptococcus pyogenesBacterial ProteinsHemeRecombinant Fusion ProteinsEPRGASheme stackingiron acquisitionmetal-binding proteinsmultimeric heme complexationprotein quaternary structureresonance Raman spectroscopyStreptococcus

Identifiers

PMID33494451
PMCPMC7865249

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.