Evidence map›Paper›PMID 33494422›Full record

ArticleInternational journal of environmental research and public health2021

Additive Manufacturing of Resected Oral and Oropharyngeal Tissue: A Pilot Study.

Alexandria L Irace, Anne Koivuholma, Eero Huotilainen, Jaana Hagström, Katri Aro, Mika Salmi, Antti Markkola, Heli Sistonen, Timo Atula, Antti A Mäkitie

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 65% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Alexandria L IraceDepartment of Otorhinolaryngology-Head and Neck Surgery, HUS Helsinki University Hospital, University of Helsinki, P.O.Box 263, FI-00029 HUS Helsinki, Finland.ORCID 0000-0003-4758-3146
Anne KoivuholmaDepartment of Otorhinolaryngology-Head and Neck Surgery, HUS Helsinki University Hospital, University of Helsinki, P.O.Box 263, FI-00029 HUS Helsinki, Finland.ORCID 0000-0002-2590-2225
Eero HuotilainenDepartment of Mechanical Engineering, Aalto University, P.O.Box 14100, FI-00076 Aalto Espoo, Finland.
Jaana HagströmDepartment of Pathology, HUS Helsinki University Hospital, University of Helsinki, P.O. Box 21, Haartmaninkatu 3, FI-00029 HUS Helsinki, Finland.ORCID 0000-0001-6079-7881
Katri AroDepartment of Otorhinolaryngology-Head and Neck Surgery, HUS Helsinki University Hospital, University of Helsinki, P.O.Box 263, FI-00029 HUS Helsinki, Finland.ORCID 0000-0001-8103-5237
Mika SalmiDepartment of Mechanical Engineering, Aalto University, P.O.Box 14100, FI-00076 Aalto Espoo, Finland.ORCID 0000-0002-7295-3551
Antti MarkkolaDepartment of Imaging, HUS Helsinki University Hospital, University of Helsinki, FI-00029 HUS Helsinki, Finland.
Heli SistonenDepartment of Imaging, HUS Helsinki University Hospital, University of Helsinki, FI-00029 HUS Helsinki, Finland.ORCID 0000-0003-0224-9750
Timo AtulaDepartment of Otorhinolaryngology-Head and Neck Surgery, HUS Helsinki University Hospital, University of Helsinki, P.O.Box 263, FI-00029 HUS Helsinki, Finland.ORCID 0000-0002-6560-1128
Antti A MäkitieDepartment of Otorhinolaryngology-Head and Neck Surgery, HUS Helsinki University Hospital, University of Helsinki, P.O.Box 263, FI-00029 HUS Helsinki, Finland.ORCID 0000-0002-0451-2404
University of Helsinki · FIAalto University · FIKarolinska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Better visualization of tumor structure and orientation are needed in the postoperative setting. We aimed to assess the feasibility of a system in which oral and oropharyngeal tumors are resected, photographed, 3D modeled, and printed using additive manufacturing techniques. Three patients diagnosed with oral/oropharyngeal cancer were included. All patients underwent preoperative magnetic resonance imaging followed by resection. In the operating room (OR), the resected tissue block was photographed using a smartphone. Digital photos were imported into Agisoft Photoscan to produce a digital 3D model of the resected tissue. Physical models were then printed using binder jetting techniques. The aforementioned process was applied in pilot cases including carcinomas of the tongue and larynx. The number of photographs taken for each case ranged from 63 to 195. The printing time for the physical models ranged from 2 to 9 h, costs ranging from 25 to 141 EUR (28 to 161 USD). Digital photography may be used to additively manufacture models of resected oral/oropharyngeal tumors in an easy, accessible and efficient fashion. The model may be used in interdisciplinary discussion regarding postoperative care to improve understanding and collaboration, but further investigation in prospective studies is required.

Indexed as

Oropharyngeal NeoplasmsPrinting, Three-DimensionalHumansMagnetic Resonance ImagingPilot ProjectsProspective Studies3D imagingadditive manufacturinghead and neck surgeryrapid manufacturingstereolithographysurgical oncology

Identifiers

PMID33494422
PMCPMC7908081
OpenAlexW3122226535

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.