Evidence map›Paper›PMID 33494402›Full record

ReviewMarine drugs2021

Marine Pharmacology in 2016-2017: Marine Compounds with Antibacterial, Antidiabetic, Antifungal, Anti-Inflammatory, Antiprotozoal, Antituberculosis and Antiviral Activities; Affecting the Immune and Nervous Systems, and Other Miscellaneous Mechanisms of Action.

Alejandro M S Mayer, Aimee J Guerrero, Abimael D Rodríguez, Orazio Taglialatela-Scafati, Fumiaki Nakamura, Nobuhiro Fusetani

Open access · goldAbstract readReview
In one paragraph

Review in Marine drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Antimicrobial Resistance Patterns of ESBL-ProducingAntibiotics (Basel, Switzerland) · 2025
    Article
  7. Voltage-Gated KMarine drugs · 2024
    Review
  8. Review
  9. Review
  10. Use of marine occurrent extracts to enhance the stability of dentin extracellular matrix.Journal of the mechanical behavior of biomedical materials · 2024
    Article
  11. Marine-derived Compounds: A Powerful Platform for the Treatment of Alzheimer's Disease.Central nervous system agents in medicinal chemistry · 2024
    Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. The Key Role of Lysosomal Protease Cathepsins in Viral Infections.International journal of molecular sciences · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 4 countries.

Alejandro M S MayerDepartment of Pharmacology, College of Graduate Studies, Midwestern University, 555 31st Street, Downers Grove, IL 60515, USA.ORCID 0000-0002-8358-4528
Aimee J GuerreroDepartment of Pharmacology, College of Graduate Studies, Midwestern University, 555 31st Street, Downers Grove, IL 60515, USA.
Abimael D RodríguezMolecular Sciences Research Center, University of Puerto Rico, 1390 Ponce de León Avenue, San Juan, PR 00926, USA.
Orazio Taglialatela-ScafatiDepartment of Pharmacy, University of Naples Federico II, Via D. Montesano 49, I-80131 Napoli, Italy.ORCID 0000-0001-8010-0180
Fumiaki NakamuraDepartment of Chemistry and Biochemistry, Graduate School of Advanced Science and Engineering, Waseda University, 3-4-1 Okubo, Shinjuku-ku, Tokyo 169-8555, Japan.
Nobuhiro FusetaniFisheries and Oceans Hakodate, Hakodate 041-8611, Japan.
Midwestern University · USHakodate University · JPUniversity of Naples Federico II · ITUniversity of Puerto Rico System · PRWaseda University · JP

Funding

Midwestern University Not ApplicableNIH-SC1 Award of the University of Puerto Rico Grant 1SC1GM086271-01A1Regione Campania-POR Campania FESR 2014/2020 B61G18000470007
6 · The paper itself

Abstract

The review of the 2016-2017 marine pharmacology literature was prepared in a manner similar as the 10 prior reviews of this series. Preclinical marine pharmacology research during 2016-2017 assessed 313 marine compounds with novel pharmacology reported by a growing number of investigators from 54 countries. The peer-reviewed literature reported antibacterial, antifungal, antiprotozoal, antituberculosis, and antiviral activities for 123 marine natural products, 111 marine compounds with antidiabetic and anti-inflammatory activities as well as affecting the immune and nervous system, while in contrast 79 marine compounds displayed miscellaneous mechanisms of action which upon further investigation may contribute to several pharmacological classes. Therefore, in 2016-2017, the preclinical marine natural product pharmacology pipeline generated both novel pharmacology as well as potentially new lead compounds for the growing clinical marine pharmaceutical pipeline, and thus sustained with its contributions the global research for novel and effective therapeutic strategies for multiple disease categories.

Indexed as

AnimalsAnti-Bacterial AgentsAntifungal AgentsAnti-Inflammatory AgentsAntiprotozoal AgentsAntitubercular AgentsAntiviral AgentsAquatic OrganismsBiological ProductsHumansHypoglycemic AgentsImmune SystemNervous SystemPharmacological and Toxicological PhenomenaAnti-Bacterial AgentsAntifungal AgentsAnti-Inflammatory AgentsAntiprotozoal AgentsAntitubercular AgentsAntiviral AgentsBiological ProductsHypoglycemic Agentschemicaldrugmarinenatural productpharmaceuticalpharmacologypipelinepreclinicalreviewseatoxicology

Identifiers

PMID33494402
PMCPMC7910995
OpenAlexW3123656563

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.