ArticleJournal of clinical medicine2021
Differences in Penile Hemodynamic Profiles in Patients with Erectile Dysfunction and Anxiety.
Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 13 citations in OpenAlex.
- Long-term high-dose L-arginine supplementation in patients with vasculogenic erectile dysfunction: a multicentre, double-blind, randomized, placebo-controlled clinical trial.Journal of endocrinological investigation · 2022Trial
- Setting the mood: improving patient satisfaction and clinic efficiency during penile duplex doppler ultrasound assessment.International journal of impotence research · 2026Article
- Clinical performance of a novel brief erectile dysfunction scale and comparison with the international index of erectile function-5.Frontiers in public health · 2026Article
- The feasibility study of shear wave elastography in the diagnosis of erectile dysfunction.Scientific reports · 2024Article
- Influence of personality disorders on sexual behaviours and response to treatment of psychogenic erectile dysfunction in phosphodiesterase 5 inhibitor non-responders.Frontiers in psychology · 2024Article
- New Challenges in Sexuality and Sexual Dysfunction.Journal of clinical medicine · 2022Article
- Validation of the Center of Applied Psychology Female Sexuality Questionnaire (CAPFS-Q).Journal of clinical medicine · 2021Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPenile echo-color Doppler ultrasound (PCDU) is the gold standard for the diagnosis of arterial erectile dysfunction (ED). Its reliability in patients with anxiety was questioned, due to false-positive results.
aimTo assess the penile hemodynamic response to intracavernous injection (ICI) of alprostadil in patients with anxiety-related ED.
methodsPatients with non-organic ED and a 5-item International Index of Erectile Function (IIEF-5) score ranging between 5 and 7 were enrolled. They were asked to compile the 7-item Generalized Anxiety Disorder (GAD-7) questionnaire to assess the degree of anxiety and were divided according to the GAD-7 score in Group 1 with minimal level of anxiety (
resultsIn penile flaccidity, the patients showed a mean PSV of 8.0 ± 4.0 cm/s. The degree of anxiety was found to significantly influence both PSV and EDV at all assessed time-points. Particularly, it was negatively associated with the PSV at time 5 (
conclusionIf further studies confirm the existence of a distinct hemodynamic profile in patients with severe anxiety, sampling the PSV and the EDV values could be proposed, for detecting patients with severe anxiety-related ED. Dynamic PCDU could be considered an accurate diagnostic test in patients with non-organic ED, since zero false-positive results were found in the present study. PSV in the flaccid state is not able to discriminate between arterial- or non-organic ED.
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